Prevention, Management and Rehabilitation of Knee Osteoarthritis at the Workplace

Knee Osteoarthritis Clinical Trial

Official title:

Prevention, Management and Rehabilitation of Knee Osteoarthritis at the Workplace

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05822401
• Other study ID #: 10429
• Secondary ID: H-22016339
• Status: Not yet recruiting
• Phase: N/A
• Start date: April 11, 2023
• Est. completion date: December 31, 2023

Study information

• Verified date: April 2023
• Source: National Research Centre for the Working Environment, Denmark
• Contact: Sebastian Skovlund
• Phone: 40385166
• Email: svs[@]nfa.dk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this intervention study is to assess the effect of blood flow restricted (BFR) exercise integrated into the daily work tasks among hospital workers with or at increased risk of chronic knee pain.

The main questions are:

Can BFR exercise integrated into the daily work tasks reduce knee pain (primary outcome) and improve function and work ability among hospital workers with or at increased risk of chronic knee pain? Participants in the intervention group will for shorts bouts during their workdays integrate BFR into their daily work tasks involving walking, whereas the control group will continue as usual.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 80
• Est. completion date: December 31, 2023
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 67 Years

Eligibility

Inclusion Criteria:

• Hospital workers working at least 20 hours per week with or without chronic knee pain (>3 months)

Exclusion Criteria:

• Life-threatening disease

• Conditions where BFR training may be contraindicated, e.g. pregnancy, cancer, diabetes, major cardiovascular disease, current, previous or family history of clotting disorders, recent immobilization, major surgery or injections into the joint (i.e. corticosteroid injection)

• Systolic/diastolic blood pressure above 160/100 mmHg

Related Conditions & MeSH terms

• Knee Discomfort
• Knee Osteoarthritis
• Knee Pain Chronic
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Behavioral:
• Blood flow restriction (BFR)
Blood flow restricted training integrated into the daily work tasks for 8 weeks.
• Usual care (control)
Will continue their work as usual

Locations

Country	Name	City	State
n/a

Sponsors (3)

Lead Sponsor	Collaborator
National Research Centre for the Working Environment, Denmark	University Hospital Bispebjerg and Frederiksberg, University of Southern Denmark

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Work-limiting pain	Rating of the degree of work limitations due to pain	Change pre-post 8 weeks of intervention
Other	Work-related fatigue	Rating af work-related fatigue in different body parts	Change pre-post 8 weeks of intervention
Primary	Pain intensity	Change in worst knee pain intensity during the last week rated on a 11-point numeric rating scale (NRS)	Change pre-post 8 weeks of intervention
Secondary	Functional performance	30-s chair-stand test, 40 m fast-paced walk test, a stair-climb test, maximal isometric knee extensor muscle strength	Change pre-post 8 weeks of intervention
Secondary	Work ability	Single-item on physical work ability derived from the Work Ability Index (WAI)	Change pre-post 8 weeks of intervention