Measuring Synovial Fluid Components

Status Active, not recruiting

Clinical Trial Summary

Participants with grade 3 and 4 knee osteoarthritis will recieve aspiration of synoivial fluid, and then receive either dextrose, hemaotopoietic stem cell, or platelet rich plasma, or no injection. The synovial fluid will be analyzed for changes in components.

Clinical Trial Description

80 participants with grade 3 and 4 symptomatic knee osteoarthritis, with a visable effusion, will receive aspiration of 3 ml of synovial fluid from the suprapatellar pouch, followed by either injection with 10 mL of 12.5% dextrose, 10 cc hematopoietic stem cells, 10cc PRP, or no injection into the suprapatellar pouch. They will then receive aspiration of 3 ml of synovial fluid at 2 days and either 7 days (for dextrose injected or no injection) or 14 days (stem cell and PRP injected) days post injection. These synovial samples will be analyzed for a change in components. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05416255
Study type	Interventional
Source	Dharma Bioscience
Contact
Status	Active, not recruiting
Phase	N/A
Start date	April 1, 2022
Completion date	December 31, 2022

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