Knee Osteoarthritis Clinical Trial
Official title:
Optimizing Movement After Anterior Cruciate Ligament Injury
Verified date | June 2024 |
Source | University of Nebraska |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will evaluate if a visual biofeedback program leads to improved knee outcomes after anterior cruciate ligament reconstruction. Outcome measures will include biomechanical movement patterns and markers of knee osteoarthritis on magnetic resonance imaging.
Status | Active, not recruiting |
Enrollment | 34 |
Est. completion date | December 2024 |
Est. primary completion date | June 5, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 13 Years to 35 Years |
Eligibility | Inclusion Criteria: - acute ACL injury in the past 6 months - have had ACL reconstruction in the past month or have a planned ACL reconstruction Exclusion Criteria: - previous knee injury or surgery (contralateral knee) - body mass index over 35 kg/m2 - concomitant posterior cruciate ligament reconstruction or cartilage procedure that include extended weightbearing restrictions and/or changes to cartilage structure - current pregnancy - planned pregnancy during study duration |
Country | Name | City | State |
---|---|---|---|
United States | University of Nebraska Medical Center | Omaha | Nebraska |
Lead Sponsor | Collaborator |
---|---|
University of Nebraska |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Knee flexion moment impulse | Between-limb ratio of knee flexion moment impulse during descent and ascent phase of bilateral squat | Immediately after the intervention | |
Primary | Cartilage T2 relaxation time | Percent change in cartilage T2 relaxation time from 2 weeks to 6 months after ACL reconstruction | 6 months after ACL reconstruction | |
Secondary | Knee flexion moment impulse | Between-limb ratio of knee flexion moment impulse during descent and ascent phase of bilateral squat | 6 months after ACL reconstruction | |
Secondary | Peak knee flexion moment | Between-limb ratio of peak flexion moment during gait | Immediately after the intervention | |
Secondary | Peak knee flexion moment | Between-limb ratio of peak flexion moment during gait | 6 months after ACL reconstruction | |
Secondary | Quadriceps strength | Between-limb ratio of isometric and isokinetic quadriceps strength | Immediately after the intervention | |
Secondary | Quadriceps strength | Between-limb ratio of isometric and isokinetic quadriceps strength | 6 months after ACL reconstruction |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04651673 -
Prescribed Knee Brace Treatments for Osteoarthritis of the Knee (Knee OA)
|
||
Completed |
NCT05677399 -
Knee Osteoarthritis Treatment With Peloidotherapy and Aquatic Exercise.
|
N/A | |
Active, not recruiting |
NCT04043819 -
Evaluation of Safety and Exploratory Efficacy of an Autologous Adipose-derived Cell Therapy Product for Treatment of Single Knee Osteoarthritis
|
Phase 1 | |
Recruiting |
NCT06000410 -
A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
|
Phase 3 | |
Completed |
NCT05014542 -
Needling Techniques for Knee Osteoarthritis
|
N/A | |
Recruiting |
NCT05892133 -
Prehabilitation Effect on Function and Patient Satisfaction Following Total Knee Arthroplasty
|
N/A | |
Recruiting |
NCT05528965 -
Parallel Versus Perpendicular Technique for Genicular Radiofrequency
|
N/A | |
Active, not recruiting |
NCT03472300 -
Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals
|
||
Active, not recruiting |
NCT02003976 -
A Randomized Trial Comparing High Tibial Osteotomy Plus Non-Surgical Treatment and Non-Surgical Treatment Alone
|
N/A | |
Active, not recruiting |
NCT04017533 -
Stability of Uncemented Medially Stabilized TKA
|
N/A | |
Completed |
NCT04779164 -
The Relation Between Abdominal Obesity, Type 2 Diabetes Mellitus and Knee Osteoarthritis
|
N/A | |
Recruiting |
NCT04006314 -
Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis
|
N/A | |
Recruiting |
NCT05423587 -
Genicular Artery Embolisation for Knee Osteoarthritis II
|
N/A | |
Enrolling by invitation |
NCT04145401 -
Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK
|
||
Active, not recruiting |
NCT03781843 -
Effects of Genicular Nerve Block in Knee Osteoarthritis
|
N/A | |
Completed |
NCT05974501 -
Pre vs Post Block in Total Knee Arthroplasty (TKA)
|
Phase 4 | |
Completed |
NCT05324163 -
Evaluate Efficacy and Safety of X0002 in Treatment of Knee Osteoarthritis
|
Phase 3 | |
Completed |
NCT05529914 -
Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis
|
N/A | |
Recruiting |
NCT05693493 -
Can Proprioceptive Knee Brace Improve Functional Outcome Following TKA?
|
N/A | |
Not yet recruiting |
NCT05510648 -
Evaluation of the Effect of High-intensity Laser Therapy in Knee Osteoarthritis
|
N/A |