Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis

Knee Osteoarthritis Clinical Trial

Official title:

Long Term Effects of Mulligan Mobilization With Movement Versus Macquarie Injury Management Group on Function and Pain of Knee Osteoarthritis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04818307
• Other study ID #: REC/Lhr/1064
• Status: Completed
• Phase: N/A
• Start date: April 1, 2020
• Est. completion date: December 30, 2020

Study information

• Verified date: August 2021
• Source: Riphah International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Knee pain is one of the most usual pain that commonly affects people especially in the late age. It can be caused by osteoarthritis, poor posture or sitting position, bad bending or improper lifting. It is usually not caused by a serious illness. It is the most common cause of disability. To compare the long term effects of Mulligan Mobilization with Movement versus Macquarie Injury Management Group on pain and function of knee osteoarthritis.

Description:

It was a randomized clinical trial conducted in Revival Physiotherapy Center, Lahore. A convenient sample of 26 diagnosed patients with osteoarthritis was included in the study. Subjects were randomly distributed in to two groups with use of flip coin method Group of randomization. Group 1 patients got MIMG with routine physical therapy and Group 2 got MWM with routine physical therapy. Visual analogue Scale (VAS),Non modified WOMAC were used to assess all patients before and after 4 weeks of intervention. Statistical analysis was computed by SPSS 20.0.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 26
• Est. completion date: December 30, 2020
• Est. primary completion date: November 30, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years and older

Eligibility

Inclusion Criteria:

• ACR criteria for knee will be over age 50
• less than 30 minutes of morning stiffness,
• Crepitus on active motion,
• Tenderness
• Enlargement
• No palpable warmth of synovium.
• Osteoarthritis grade 1 and 2 by Kelly-green and Lawrence method.

Exclusion Criteria:

• Any surgical procedure done in past 6 months and metal implants in lower extremity.
• Any infection and neoplastic disorder.
• Post traumatic knee stiffness.
• Secondary knee O A peripheral vascular disease

Related Conditions & MeSH terms

• Knee Osteoarthritis
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Other:
• Macquarie Injury Management group
Group A was treated by MIMG (soft tissue mobilization) with base line treatment (Hot pack for 10 mint, Quadriceps Isometrics, Stretching). For the application of technique subject lies supine with extended knee, therapist places both hands on the knee and gently apply soft tissue release. This procedure was applied for 2 to 3 minutes.
• Mulligan Mobilization with Movement
Group B was treated by Mulligan Mobilization with movement with base line treatment (Hot Pack for 10 mints, Quadriceps Isometrics, Stretching). For the application of technique subject lies supine with 30 degree knee flexion, therapist places right hand below the knee and left hand above the knee. Apply the lateral glide on the joint. This procedure was applied for 3 times.

Locations

Country	Name	City	State
Pakistan	Riphah Rehabilitation Center	Lahore	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

References & Publications (6)

Alshami AM. Knee osteoarthritis related pain: a narrative review of diagnosis and treatment. Int J Health Sci (Qassim). 2014 Jan;8(1):85-104. Review. — View Citation

Bhatia D, Bejarano T, Novo M. Current interventions in the management of knee osteoarthritis. J Pharm Bioallied Sci. 2013 Jan;5(1):30-8. doi: 10.4103/0975-7406.106561. — View Citation

Cooper C, McAlindon T, Coggon D, Egger P, Dieppe P. Occupational activity and osteoarthritis of the knee. Ann Rheum Dis. 1994 Feb;53(2):90-3. — View Citation

Felson DT, Gale DR, Elon Gale M, Niu J, Hunter DJ, Goggins J, Lavalley MP. Osteophytes and progression of knee osteoarthritis. Rheumatology (Oxford). 2005 Jan;44(1):100-4. Epub 2004 Sep 20. — View Citation

Felson DT. The epidemiology of knee osteoarthritis: results from the Framingham Osteoarthritis Study. Semin Arthritis Rheum. 1990 Dec;20(3 Suppl 1):42-50. — View Citation

Kandada S, Heggannavar A. Effect of Mulligan's MWM versus Macquarie Injury Management Group (MIMG) protocol on pain and function in osteoarthritis of knee: a randomised clinical trial. IJTRR. 2015;4(4):125-31.

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Visual Analogue scale	The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."	6 months
Primary	WOMAC	The scores for each subscale are summed up, with a possible score range of 0-20 for Pain, 0-8 for Stiffness, and 0-68 for Physical Function. Usually a sum of the scores for all three subscales gives a total WOMAC score, however there are other methods that have been used to combine scores.	6 months