IPICK Blocking for TKA With Moderate Flexion Contracture

Knee Osteoarthritis Clinical Trial

Official title:

IPICK Blocking for Extension Recovery in TKA With Preoperative Moderate Flexion Contracture

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04603950
• Other study ID #: QiXin2
• Status: Completed
• Phase: N/A
• Start date: November 1, 2020
• Est. completion date: March 31, 2021

Study information

• Verified date: October 2020
• Source: The First Hospital of Jilin University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Clinical effect of intermittent multiple IPICK blocking on TKA for knee osteoarthritis with flexion contracture between 5 ° and 10 °

Description:

From October 2020 to January 2021, 40 knee osteoarthritis patients with flexion contracture between 5 ° and 10 ° total knee arthroplasty are enrolled in this study. 20 patients are treated with Adductor Canal Block + Infiltration between the Popliteal Artery and Capsule of the Knee, and 20 patients are treated with Adductor Canal Block alone.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 42
• Est. completion date: March 31, 2021
• Est. primary completion date: February 28, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years to 80 Years

Eligibility

Inclusion Criteria:

1. The diagnosis was knee osteoarthritis

2. The flexion contracture was between 5 and 10 degrees

3. ASA grade I-III

Exclusion Criteria:

1. Lower extremity neuropathy.

2. Contraindications of nerve anesthesia or regional anesthesia.

3. unable to cooperate, allergic to the drugs used in this study.

4. Non steroidal anti-inflammatory drugs are not tolerated.

5. chronic opioid consumption (daily or almost daily use)

Related Conditions & MeSH terms

• Anesthesia, Local
• Contracture
• Flexion Contracture of Knees
• Knee Osteoarthritis
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Procedure:
• CACB+IPACK
continue adductor canal block plus Infiltration between the Popliteal Artery and Capsule of the Knee
• CACB
continue adductor canal block

Locations

Country	Name	City	State
China	The First Hospital of Jilin University	Changchun

Sponsors (1)

Lead Sponsor	Collaborator
The First Hospital of Jilin University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	evaluation of pain	Visual Analog Score for pain at rest, straightening, flexion at 45 ° and walking, the minimum and maximum values are 0 to 10, higher scores mean a worse outcome.	6 hours after surgery
Primary	evaluation of pain	Visual Analog Score for pain at rest, straightening, flexion at 45 ° and walking, the minimum and maximum values are 0 to 10, higher scores mean a worse outcome.	postoperative day 1
Primary	evaluation of pain	Visual Analog Score for pain at rest, straightening, flexion at 45 ° and walking, the minimum and maximum values are 0 to 10, higher scores mean a worse outcome.	postoperative day 2
Primary	evaluation of pain	Visual Analog Score for pain at rest, straightening, flexion at 45 ° and walking, the minimum and maximum values are 0 to 10, higher scores mean a worse outcome.	postoperative day 3
Primary	extension angle	degree of the extension of knee	before surgery
Primary	extension angle	degree of the extension of knee	0 hour after surgery
Primary	extension angle	degree of the extension of knee	6 hour after surgery
Primary	extension angle	degree of the extension of knee	postoperative day 1
Primary	extension angle	degree of the extension of knee	postoperative day 2
Primary	extension angle	degree of the extension of knee	postoperative day 3
Secondary	range of motion	degree of range of motion from extension to flexion of knee	6 hour after surgery
Secondary	range of motion	degree of range of motion from extension to flexion of knee	postoperative day 1
Secondary	range of motion	degree of range of motion from extension to flexion of knee	postoperative day 2
Secondary	range of motion	degree of range of motion from extension to flexion of knee	postoperative day 3
Secondary	opioid consumption	total opioid consumption measured by milliliter.	through hospitalization, an average of 7 days
Secondary	nerve block related symptoms	the incidence of numbness of the nerve related skin	through hospitalization, an average of 7 days
Secondary	postoperative acute pain	number of cases whose Visual Analog Score for pain was more than 5	through hospitalization, an average of 7 days