Mesenchymal Stem Cell Transplantation for Osteoarthritis

Status Terminated

Clinical Trial Summary

The purpose of this study is to explore the efficacy and safety of autologous bone marrow-derived mesenchymal stem cells (BMSCs) plus autologous platelet rich plasma (PRP) in the treatment of severe knee osteoarthritis.

Clinical Trial Description

This is a single centered, randomized, single blind phase II clinical study. Patients will be divided into two groups of case and control. Patients of case group will receive intra-articular injection of autologous BMSCs suspended in 3 ml autologous PRP for 3 times, patients of control group will receive intra-articular injection of 3 ml of autologous PRP for 3 times. The investigators designed this clinical study to evaluate therapeutic effects of BM-MSCs in patients with severe knee osteoarthritis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03969680
Study type	Interventional
Source	Yantai Yuhuangding Hospital
Contact
Status	Terminated
Phase	N/A
Start date	July 8, 2019
Completion date	December 28, 2023

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