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Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury

Knee Osteoarthritis Clinical Trial

Official title:
Efficacy and Safety Research of Autologous Adipose-derived Mesenchymal Stem Cell Gel in the Treatment of Cartilage Damage in the Knee

Clinical Trial Summary

This study was aimed to evaluate the efficacy and safety of Autologous Adipose-derived Mesenchymal Stem Cell Gel combine with High tibial osteotomy therapy in the treatment of cartilage damage in the knee. Investigator believe that this method will enable patients to recover better knee function and more repair of knee cartilage.

Clinical Trial Description

The patients who will underwent high tibial osteotomy were randomly divided into the experimental group and the control group. Abdominal fat extraction before operation in experimental group to prepare Adipose-derived Mesenchymal Stem Cell Gel, while the control group only underwent high tibial osteotomy. One month after operation, the experimental group was injected with Adipose-derived Mesenchymal Stem Cell Gel into the joint cavity, and the control group was injected with sodium hyaluronate in the joint cavity. Two groups of patients were followed up. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03955497
Study type Interventional
Source Qilu Hospital of Shandong University
Contact Songlin Li, MD
Phone 0531-82166541
Email bysonglin@126.com
Status Recruiting
Phase Phase 1/Phase 2
Start date October 1, 2018
Completion date December 1, 2022
View Details
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