Maximizing Analgesia to Reduce Pain in Knee Osteoarthritis

Status Completed

Clinical Trial Summary

This research is being done to evaluate whether combining medications that are FDA approved, but have not yet been approved for combination treatment, can be effective in reducing pain.

Clinical Trial Description

This study will evaluate whether a combination of pharmacotherapies can effectively alleviate pain. Subjects will complete two screening sessions before completing four study sessions that will occur once weekly. Participants will receive double blind doses of study medications the morning of each experimental session day and will undergo standardized pain testing, physical functioning assessment, blood draws, ratings of drug effects and cognitive testing. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03098563
Study type	Interventional
Source	Johns Hopkins University
Contact
Status	Completed
Phase	Phase 2
Start date	November 1, 2017
Completion date	November 27, 2023

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