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Autologous Stromal Vascular Fraction of Cells for Treatment of Knee Articular Cartilage Dystrophy

Knee Osteoarthritis Clinical Trial

Official title:
Evaluation of Safety and Effectiveness of Intraarticular Administration of Autologous Stromal Vascular Fraction of Cells for Treatment of Knee Articular Cartilage Dystrophy

Clinical Trial Summary

Stromal vascular fraction of cells (SVF) will be extracted from lipoaspirate by enzymatic digestion. SVF will be administered in a single dose intraarticularly 4 weeks after arthroscopic debridement. All patients will receive cell therapy.This is a single arm study with no control.

Clinical Trial Description

Patients undergone arthroscopic debridement for knee osteoarthritis will be subjected to abdominal liposuction under local anaesthesia. Harvested adipose tissue will be processed according to patent pending technology based on enzymatic digestion, washing and concentration of cell pellet in 5 ml of Hartmann's solution. Isolated SVF will be administered in a single dose into anterior part of knee joint cavity 28 days after arthroscopy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02827851
Study type Interventional
Source Central Clinical Hospital with Outpatient Health Center of Business Administration for the President of Russian Federati
Contact
Status Enrolling by invitation
Phase Phase 2
Start date May 2016
Completion date November 2018
View Details
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