Knee Osteoarthritis Clinical Trial
Official title:
Intraarticular Injections of Platelet-rich Plasma in Pain's Treatment of the Osteoarthritic Knee
Platelet-rich plasma (PRP), due to its high content of cytokines, bioactive proteins and
platelet growth factors, may contribute to diminish the pain of arthritic knee. It was also
recently recognized a regenerative cell potential improving the concentration of hyaluronic
acid and stabilizing angiogenesis in arthritic knees
This study therefore seeks to assess the analgesic power of PRP in osteoarthritic knees
intraarticularly infiltrated, and which patients would benefit most from treatment,
eliminating false expectations in the rest.
This is the first clinical trial developed following the report of the Spanish Competent Authority on May 23, 2013, considering the PRP as a medicinal product for human use and establishing minimum guarantees required of the product and the process of manufacturing. It has been conducted from the perspective of both the trauma and the specialized treatment of chronic pain anesthesiologist, and manufacturing the PRP on the premises of a Regional Centre for Transfusions, all belonging to the Public Health System and therefore without commercial interests. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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