Knee Osteoarthritis Clinical Trial
Official title:
A Controlled Comparison of Pulsed Radiofrequency Vs Physical Therapy on Treating Chronic Knee Osteoarthritis
It is estimated that nearly 27 million US adults have osteoarthritis (OA) and suffer from
pain . Pulsed Radio Frequency (PRF) is one method that has been successfully used in
treatment of various etiologies of pain. However there are limited studies and research that
prove its effectiveness in treating articular pain. The proposed study's primary aim is
determining if PRF is an effective treatment for chronic osteoarthritic knee pain. This
study hypothesizes that PRF has analgesic properties immediately after treatment and at
least 3 months afterwards compared to control treatment with physical therapy.
Additionally this research project addresses several other objectives including:
1. Provide a controlled study to determine the effectiveness of PRF for intra-articular
pain
2. Determine how effective PRF is 1 month and 3 months after treatment for articular pain.
3. Further scientific evidence on the overall effectiveness of PRF
4. Provide evidence that PRF likely has other mechanism of action besides direct nerve
stimulation of inhibitory pain pathways.
5. Compare the effectiveness of PRF vs Physical Therapy in treating chronic knee
osteoarthritis.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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