Knee Osteoarthritis Clinical Trial
Official title:
Orthopaedic Manual Physical Therapy Versus Corticosteroid Injections for Osteoarthritis of the Knee
The purpose of this study is to compare an orthopaedic manual physical therapy (OMPT) to corticosteroid injection for the management of knee osteoarthritis.
The purpose of this study is to compare a commonly offered clinical approach of a series of
intra-articular steroid injections to an orthopaedic manual physical therapy (OMPT) approach
consisting of manually applied passive movement and reinforcing exercise for the treatment of
osteoarthritis of the knee (knee OA). A second purpose is to validate a clinical prediction
rule (CPR) for patients unlikely to respond to the orthopaedic manual physical therapy
approach in a pre-planned secondary analysis of data from the randomized clinical trial.
Aim 1: To see if there is a significant difference in pain and function lasting out to 1 year
for patients that receive a clinical approach consisting of a series of intra-articular
steroid injections compared to those that receive a clinical approach consisting of
orthopaedic manual physical therapy.
Aim 2: To validate a clinical prediction rule of characteristics identified in a previous
preliminary study that predicted which patients with knee OA would be unlikely to respond to
OMPT.
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