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Comparison of Three Tourniquet Application Methods in Primary Total Knee Arthroplasty Surgery

Knee Osteoarthritis Clinical Trial

Official title:
Influence of the Intraoperative Tourniquet Application Method on the Perioperative Blood Loss, Frequency of Transfusion and Close Postoperative Outcomes in Primary Total Knee Arthroplasty Patients

Clinical Trial Summary

Different strategies of tourniquet application during elective primary total knee arthroplasty are thought to be associated with different outcomes. In that context, the study investigates different tactics in the search of optimal application of the tourniquet and the related fluid management during 24 perioperative hours.

Clinical Trial Description

The optimal application of tourniquet should reduce perioperative blood loss, create bloodless operative field, improve cementing technique and shorten surgery time. Meanwhile, inadequate application may increase the risk of deep vein thrombosis and pulmonary thromboembolism. Previous attempts to compare the tourniquet strategies in respect to the perioperative blood loss did not show significant difference. The investigators use the volume loading test aiming to optimize the fluid status and obtain the hemoglobin concentration in the conditions of standardized plasma dilution. The test is deployed just before the surgery and after postoperative 24 hrs in ICU. Functional outcomes and possible length of hospital stay is also evaluated. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01355900
Study type Interventional
Source Vilnius University
Contact
Status Completed
Phase N/A
Start date January 2010
Completion date January 2014
View Details
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