Knee Osteoarthritis Clinical Trial
The aim of this study is to evaluate the outcome of specific repetitive biomechanical
perturbation training on motor patterns.
The first hypothesis of this project is that footwear derived biomechanical challenges will
convey active and passive matching biomechanical responses (i.e. kinetic, kinematic and
electromyographic) trough out the musculoskeletal kinematic chain.
The second hypothesis of the project is that repetitive exposure to in-situ (trough out the
gait sickle) introduction to a biomechanical stimulus would generate a process of motor
learning thus conveying plasticity of existing locomotor patterns and gait strategies.
Design: Prospective, case control Setting: subjects will undergo a tailored training program utilizing a novel biomechanical system comprising four modular elements attached onto foot-worn platforms (APOS system, Apos - Sports and Medical Technologies Ltd. Hertzlia, Israel) which conveys perturbation throughout the gait sickle. Pre and post training level walking will be examined via: (1) a three-dimensional motion analysis system and (2) ground reaction force analysis using force platforms (3) Electro-Myography system. Each subject will be examined in 4 different settings Patients will then participate in continued biomechanical perturbation training for 3-6 month and will then undergo a second gait examination Ages Eligible for Study: 50 Years - 75 Years, Genders Eligible for Study: None Accepts patients suffering from medial compartment knee osteoarthritis ;
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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