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Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis

Knee Osteoarthritis Clinical Trial

Official title:
Prospective Assessment of the Efficacy of Intra-Articular Hyaluronate to Affect Extracellular Matrix Changes in Patients With Osteoarthritis

Clinical Trial Summary

This study looks at the effect of an injectable medication called Hyalgan on the cartilage of the knee in people who have osteoarthritis ("wear and tear arthritis") of the knee. Hyalgan is a medication which is injected into the knee, and is FDA approved to treat knee arthritis. We will be using magnetic resonance imaging (MRI) and x-rays to look at knee cartilage to see how it responds over the course of a year to the injections. A comparison to patients taking oral pain medication will be made.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00323778
Study type Interventional
Source Hospital for Special Surgery, New York
Contact
Status Terminated
Phase Phase 3
Start date May 2006
View Details
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