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Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

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NCT ID: NCT05160532 Recruiting - Knee Osteoarthritis Clinical Trials

Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis

Start date: April 10, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this research is to learn more about treating Symptomatic Knee Osteoarthritis (OA) with an ultrasound-guided hypertonic dextrose injection. Researchers would like to determine best practice for injection frequency and effectiveness of the dextrose injection for symptomatic knee OA.

NCT ID: NCT05156216 Completed - Knee Osteoarthritis Clinical Trials

Comparative Effect of Two Educational Videos for People With Knee Osteoarthritis (vidEO)

vidEO
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Education is an important part of knee osteoarthritis management. The aim of education is to help people with knee osteoarthritis make the best choices for them in terms of their treatment and lifestyle behaviours. Traditional education that describes the condition simplistically in terms of the joint damage and describes the cause of osteoarthritis solely with respect to loading through the joint can lead to activity avoidance and pessimism about the future progression of symptoms. An alternative is to provide the information about knee osteoarthritis management with the aim of giving hope for the future and building motivation and confidence to be physically active. This study will compare two educational videos that cover the same topics but with a contrasting 'discourse'. The experimental video has an 'empowerment and participatory' discourse, while the comparator or control video has a typical 'disease and impairment' discourse. The experimental video minimises mention of joint damage and instead corrects misconceptions about knee osteoarthritis, addresses common barriers to physical activity and incorporates behaviour change techniques such as social learning and modelling of desired behaviours. In this randomised controlled trial, people who report a history of knee problems consistent with knee osteoarthritis will complete questionnaires to determine their self-efficacy for managing knee osteoarthritis pain and their fear of movement. The participants will also be asked about their expectations for the future, their level of motivation to be physically active, and their knowledge about knee osteoarthritis. Participants will then be allocated one of the videos and asked to watch it before repeating the questionnaires.

NCT ID: NCT05151627 Completed - Knee Osteoarthritis Clinical Trials

The Effectiveness of Kinesio Taping in Patients With Knee Osteoarthritis

Start date: June 17, 2020
Phase: N/A
Study type: Interventional

Knee osteoarthritis is the most common kind of arthritis that occurs due to degeneration of the joint articular cartilage, producing pain, stiffness, and impaired movement. Kinesio taping is a simple and inexpensive therapeutic procedure that can help with knee osteoarthritis symptoms. Kinesio taping is a high-stretch elastic adhesive material that allows the treated area to have free mobility. This technique was preferred by physical therapists for knee osteoarthritis rehabilitation because of its positive effects, such as decreased pain and increased mobility and muscular performance.

NCT ID: NCT05151315 Recruiting - Knee Osteoarthritis Clinical Trials

NitrX Total Knee Arthroplasty RSA

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Metal hypersensitivity is a recognized complication in some patients following total joint arthroplasty. This can result in a reaction to metal particles from the implants placed in the joint and cause tissue injury. The Evolution® NitrXâ„¢ (MicroPort Orthopaedics, Memphis, TN) knee implant was designed with the addition of a coating meant to create a barrier against the release of metal ions. The primary purpose of this study is to compare the Evolution and Evolution NitrX implant (implants your surgeon uses in total knee arthroplasty surgery). This study will compare the stability of these knee implants (any movement the implant makes after surgery) through the use of specialized xrays, called "radiostereometric analysis" (RSA for short). The investigators will also compare levels of circulating metal particles with blood draws and the effects of any circulating metal with MR imaging. The investigators will also be looking at the participants clinical outcomes using joint function and patient satisfaction questionnaires. A total of 50 patients will be enrolled into the study.

NCT ID: NCT05148416 Completed - Knee Osteoarthritis Clinical Trials

Effect of High Intensity Laser in Treatment of Myofascial Trigger Points in Symptomatic Knee Osteoarthritis

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This study was conducted to investigate the effect of High intensity laser therapy( HILT) on pressure pain threshold, serum cortisol level, passive knee range of motion, and changes of functional disability in patients with active myofascial trigger points(MTrPs) pain associated wit knee osteoarthritis(OA) .

NCT ID: NCT05139875 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Comparing Intra-articular Betamethasone (Diprospan) and Triamcinolone Acetonide Injection in Knee Osteoarthritis

Start date: January 1, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy of Intra-articular corticosteroid injection between Betamethasone (Diprospan) and Triamcinolone acetonide for treatment of knee osteoarthritis

NCT ID: NCT05139030 Completed - Knee Osteoarthritis Clinical Trials

Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty

Start date: January 18, 2022
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare magnitude of postsurgical analgesic effect in different groups following a single dose of study drug when administered via adductor canal block in subjects undergoing primary unilateral total knee arthroplasty.

NCT ID: NCT05137834 Active, not recruiting - Knee Osteoarthritis Clinical Trials

The Effect of Postoperative "Peanut Ball" Rehabilitation After Total Knee Replacement.

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled study is to evaluate the effect of postoperative exercise with a "peanut ball" after total knee replacement, on pain, intake of pain killers, knee function, and health-related quality of life.

NCT ID: NCT05133934 Recruiting - Knee Osteoarthritis Clinical Trials

Traditional Chinese and Western Medicine for Knee Osteoarthritis

TCMWMKOA
Start date: October 1, 2021
Phase:
Study type: Observational [Patient Registry]

A cohort study will be used to collect patient data, analyze the clinical characteristics, traditional Chinese medicine (TCM) syndromes, and treatment of knee osteoarthritis (KOA) in China to accumulate clinical data and clarify the status of KOA in the real world background. It will lay a clinical foundation for further study of KOA in the future, and bring certain clinical value for Chinese patients with KOA.

NCT ID: NCT05131048 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Home Based Hip Strengthening for Knee OA Patients

Start date: November 2021
Phase: N/A
Study type: Interventional

In knee osteoarthritis patients, weakness of hip abductor muscles is considered an important contributing factor leading to the progression of the disease.