Knee Injuries Clinical Trial
Official title:
A Phase II Trial to Investigate Clinical Efficacy of Autologous Synovial Fluid Mesenchymal Stem Cell-Derived Exosome Application in Patients With Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
Mesenchymal stem cell-derived exosomes will be developed and patented as an advanced technology platform as an autologous treatment protocol to repair damaged cartilage tissue. The fact that this treatment is obtained from an autologous source will significantly contribute to the literature in the field of personalized therapy (personalized medicine) and will pave the way for discoveries. Experiences from clinical trials may guide the use of MSC exosomes in other tissue and cell damaged pathologies and immune pathologies or chronic inflammatory diseases. This study was supported by a grant (1004, 20AG031) from The Scientific and Technological Research Council of Turkey (TUBITAK). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04554212 -
Blood Flow Restriction Training After Patellar INStability
|
N/A | |
| Completed |
NCT04815980 -
Impact of Pilates on Running Mechanics
|
N/A | |
| Not yet recruiting |
NCT05484778 -
Analysis of Balance and Functional Hop Tests Used for Return to Sports in Athletes With Lower Extremity Injuries by Dual Task Study
|
N/A | |
| Terminated |
NCT02909257 -
Motor-Sparing Femoral Nerve Block Dose
|
Phase 4 | |
| Completed |
NCT02540811 -
Clinical Evaluation of dCELL® ACL Scaffold for Reconstruction of the Anterior Cruciate Ligament
|
N/A | |
| Recruiting |
NCT03755388 -
Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant
|
N/A | |
| Recruiting |
NCT00174213 -
Validity and Reliability in Measuring Iliotibial Tract by Using Ultrasound
|
Phase 1 | |
| Completed |
NCT03202901 -
Accute Effect of B-Turmactive Both on Mild and Moderate Knee Pain on Healthy Volunteers
|
N/A | |
| Completed |
NCT06206018 -
Patient-Reported Outcome Measures in Lower Extremity Rehabilitation Program PROM_R: Impact on Health Care
|
N/A | |
| Completed |
NCT04543227 -
Opioid Laws and Pediatric Use
|
||
| Completed |
NCT06078072 -
Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions
|
||
| Completed |
NCT04956393 -
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
|
N/A | |
| Recruiting |
NCT06451510 -
Knee Osteoarthritis in the Region of Norrbotten
|
||
| Completed |
NCT04118023 -
7T MRI to Evaluate Cartilage Defects in the Knee
|
||
| Completed |
NCT03486405 -
A Randomized Control Trial: Returning to Run After Injury
|
N/A | |
| Recruiting |
NCT03858231 -
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
|
Phase 4 | |
| Recruiting |
NCT02918734 -
Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws
|
N/A | |
| Suspended |
NCT02270905 -
Clinical Evaluation of dCELL® Meniscus for Partial Replacement of the Meniscus
|
N/A | |
| Completed |
NCT01227694 -
Adult Stem Cell Therapy for Repairing Articular Cartilage in Gonarthrosis
|
Phase 1/Phase 2 | |
| Completed |
NCT00991588 -
Clinical Outcome of Posterior Cruciate Ligament (PCL) Posterolateral Reconstruction
|