Clinical Trials Logo
  1. Home
  2. Knee Injuries
  3. NCT06078072

Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions

Knee Injuries Clinical Trial

Official title:
Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions

Clinical Trial Summary

The goal of this observational study is to evaluate the combined single-step approach with biomaterials and mesenchymal stem/stromal cells in the treatment of knee articular surface lesions. The clinical analysis of the treatment outcomes, regarding postoperative improvements and safety, is going to be accompanied with laboratory analysis of the intraoperatively applied cellular products. The main hypothesis are: (1) such combined single-step procedure significantly improves patients' functioning and quality of life; (2) this therapeutic approach is safe; (3) cellular parameters of the applied filtered bone marrow aspirate (fBMA) impact treatment outcomes, among other potential predictors. Researchers will compare subjective (questionnaire) and objective (clinical examination) status of patients before and after the operation, record any potential complications and perform regression analysis to assess the influence of potential predictors on postoperative improvements.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06078072
Study type Observational
Source University Medical Centre Ljubljana
Contact
Status Completed
Phase
Start date September 1, 2022
Completion date October 31, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04554212 - Blood Flow Restriction Training After Patellar INStability N/A
Completed NCT04815980 - Impact of Pilates on Running Mechanics N/A
Not yet recruiting NCT05484778 - Analysis of Balance and Functional Hop Tests Used for Return to Sports in Athletes With Lower Extremity Injuries by Dual Task Study N/A
Terminated NCT02909257 - Motor-Sparing Femoral Nerve Block Dose Phase 4
Completed NCT02540811 - Clinical Evaluation of dCELL® ACL Scaffold for Reconstruction of the Anterior Cruciate Ligament N/A
Recruiting NCT03755388 - Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant N/A
Recruiting NCT00174213 - Validity and Reliability in Measuring Iliotibial Tract by Using Ultrasound Phase 1
Completed NCT03202901 - Accute Effect of B-Turmactive Both on Mild and Moderate Knee Pain on Healthy Volunteers N/A
Enrolling by invitation NCT06206018 - Patient-Reported Outcome Measures in Lower Extremity Rehabilitation Program PROM_R: Impact on Health Care N/A
Completed NCT04543227 - Opioid Laws and Pediatric Use
Completed NCT04956393 - The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study N/A
Completed NCT04118023 - 7T MRI to Evaluate Cartilage Defects in the Knee
Completed NCT03486405 - A Randomized Control Trial: Returning to Run After Injury N/A
Recruiting NCT03858231 - Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery Phase 4
Recruiting NCT02918734 - Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws N/A
Suspended NCT02270905 - Clinical Evaluation of dCELL® Meniscus for Partial Replacement of the Meniscus N/A
Completed NCT01227694 - Adult Stem Cell Therapy for Repairing Articular Cartilage in Gonarthrosis Phase 1/Phase 2
Completed NCT00991588 - Clinical Outcome of Posterior Cruciate Ligament (PCL) Posterolateral Reconstruction
Recruiting NCT05566561 - Para-sartorial Compartment Block in Knee Surgery N/A
Completed NCT05080894 - Virtual Reality Rehabilitation for Patients With Anterior Cruciate Ligament Reconstruction N/A