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Knee Injuries clinical trials

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NCT ID: NCT04528992 Recruiting - Knee Injuries Clinical Trials

Effects of Blood Flow Restriction (BFR) Therapy on ACL Graft Maturation

Start date: May 2024
Phase: N/A
Study type: Interventional

This is a study comparing the effects of blood flow restriction (BFR) therapy on the maturation of the Anterior Cruciate Ligament (ACL) graft after reconstruction surgery compared to physical therapy without the use of BFR.

NCT ID: NCT04366037 Recruiting - Knee Injuries Clinical Trials

Effectiveness of Proprioceptive Exercises in Soccer.

Start date: July 26, 2020
Phase: N/A
Study type: Interventional

SUMMARY Contextualization The knee is one of the joints that has more injuries reports in men's soccer. Nowadays there are different injury prevention protocols, but none of them specifically focus on the knee joint. Numerous studies have shown that proprioceptive work is more effective than traditional protocols. Objective This study aims to test the effects of a proprioceptive exercise program included as part of warm-up or cool-down in preventing knee injuries and muscle performance in youth soccer players Methodology This is a quasi-experimental study with three intervention groups. One group will be control, another group will be experimental with the intervention in the warm-up phase, and another one experimental group with the intervention in the cool-down phase. The independent variable will be the proprioceptive exercises, the dependent variables will be the dynamic balance measured with the Y Balance Test, and the muscular performance measured with Counter Movement Jump and the 40m sprint. The confounding variables will be age, height, weight, and body mass index (BMI).

NCT ID: NCT04359628 Recruiting - Heart Failure Clinical Trials

How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups?

SWEQR
Start date: January 2002
Phase:
Study type: Observational [Patient Registry]

EQ-5D is one of the most commonly employed patient-reported outcome (PRO) measures. It is included in many of the Swedish National Quality Registers (NQRs). EQ-5D health states are usually summarized using 'values' obtained from healthy members of the general public. However an alternative - which remains to be studied in detail - is the potential to use patients' self-reported overall health on the visual analogue scale as a means of capturing experience-based values. The overall aim of this project is to increase knowledge on the potential applicability of EQ VAS as a health state valuation method through assessment of its variability across and within patient groups and compared with that of the general population in Sweden. Data on nearly 700,000 patients from 12 NQRs covering a variety of diseases/conditions and from the general population will be analysed. Longitudinal studies of PROs among different patient groups will be conducted at baseline/first visit and 1-year follow-up. Descriptive analyses comparing EQ-5D health states and observed self-assessed EQ VAS within and across registers will be performed. Comparisons of the change in health state and observed EQ VAS values over one year will also be made. Regression models will be used to assess whether EQ-5D dimensions predict observed EQ VAS values to investigate patient value sets in each NQR. These will be compared across the patient groups and with the existing Swedish experience-based VAS and time trade-off (TTO) value sets obtained from the general population. This research project will provide information on the variation among different patient groups in terms of self-reported health status through EQ VAS and comparison with the general population. Knowledge on the relative importance of different dimensions of the EQ-5D to different patient groups as well as the general population will be gained in this project. The possibility of getting value sets based on patients' self-reported EQ VAS values and their comparison with value sets from experience-based general population studies will be discussed.

NCT ID: NCT04274543 Recruiting - Knee Injuries Clinical Trials

Ultrasound-Guided Injections for Meniscal Injuries in Active-Duty Military

Start date: July 1, 2019
Phase: Phase 2
Study type: Interventional

Knee injuries are common among active-duty military personnel. One of the most common knee injuries is a meniscus tear, which can have several consequences. Immediately, the soldier may be separated from the military for over one year or assigned a permanent activity limiting duty profile. Over time, meniscal tears may also increase the risk of other knee injuries, such as osteoarthritis, which is one of the most common medical reasons for discharge from active duty service. The current standard of care includes conservative treatments, such as physical therapy and rest. Once conservative treatments fail, surgery is generally the next option. However, there is limited evidence that surgery is effective and some studies suggest it can accelerate the development of osteoarthritis. The goal of this study is to evaluate the efficacy of a regenerative treatment for meniscal tears termed micro-fragmented adipose tissue in reducing pain and restoring activity levels. We will recruit active-duty military personnel and civilians with meniscal tears and provide them with either the adipose tissue treatment or a control treatment consisting of saline. We will then follow these individuals for up to one year and evaluate differences in pain and function between the two groups. The ultimate goal is to show that micro-fragmented adipose tissue is a viable alternative for the treatment of meniscal tears in active-duty military personnel.

NCT ID: NCT04163445 Recruiting - Knee Osteoarthritis Clinical Trials

Comparison of TKAs Using Force Plate Analysis

Start date: November 11, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate performance of two modern total knee arthroplasty designs using patient reported outcomes and force exhibited during various activities of daily living.

NCT ID: NCT04109638 Recruiting - Pain, Postoperative Clinical Trials

Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The primary objective of this study is to prospectively determine, at 10 days after orthopedic shoulder or knee surgery, if pulsed electromagnetic field (PEMF) therapy is beneficial in reducing patient-reported post-operative pain, as measured by visual analog scale (VAS). The amount of pain medication taken daily and the physical function outcome scores after surgery and PEMF treatment will also be measured.

NCT ID: NCT04062578 Recruiting - Clinical trials for Anterior Cruciate Ligament Injuries

Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players

Start date: September 9, 2019
Phase: N/A
Study type: Interventional

Background and justification: Women's football has a percentage of knee injury of 31.8%, and the anterior cruciate ligament lesion is between 2 and 4 times higher than the male. Injury prevention programs seek to improve the control of the neuromuscular recruitment, dynamic valgus and lumbopelvic stabilization. Recently Cibulka and Bennett have proposed a new prevention theory based on the strengthening of the external abductor and hip rotator muscles. The objective of this study is to design and carry out a physiotherapy program based on the prevention of modifiable risks factors. Design: Controlled clinical trial Methodology: 2 groups were formed, the first or experimental integrated by the female players from football team called CD Oliver (CDO), and control, integrated by the female players of the first team SD Huesca (SDH). The investigators will carried out an initial and final evaluation in which they will be collected data on variables of injury incidence, muscle length and torque. A physiotherapy program will be implemented that will consider three areas of weekly action during training, preventive force sessions, compensatory force sessions and physiotherapy sessions.

NCT ID: NCT03932838 Recruiting - Injury, Knee Clinical Trials

Descriptive Study of Multiligamentary Reconstruction of the Knee

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

Evaluation of clinical results and postoperative laxity after single-stage reconstruction of multiligamentous lesions of the knee. Comparison of two types of transplant: allograft versus autograft. There is currently little data in the clinical outcome literature after allograft reconstruction. There is one study reporting postoperative laxity assessed by dynamic radiography in the four planes (anterior, posterior, varus, valgus). No study compares postoperative laxity after allograft versus autograft reconstruction.

NCT ID: NCT03858231 Recruiting - Pain, Postoperative Clinical Trials

Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery

Start date: October 29, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to look at pain management with opioids versus non-opioids after knee arthroscopy. This study will determine 1) whether the most commonly used non-narcotic medications provide pain relief comparable with the most commonly prescribed narcotic medications in patients undergoing arthroscopic knee surgery, and 2) whether patients' characteristics (gender, pre-operative knee symptoms, workers compensation status and employment status) affect pain level following surgery or medication usage.

NCT ID: NCT03805464 Recruiting - Knee Osteoarthritis Clinical Trials

Walking Gait Biomechanics Following Knee Joint Effusion

Start date: January 29, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the sensitivity of a wearable sensor to detect changes in knee joint loading using an experimental knee joint effusion as a model for a common clinical physiological alteration in joint status. The rationale for this project is that it will establish the efficacy of an inexpensive, clinically, and publicly available device that can detect changes in biomechanical loading due to acute physiologic change in joint status. The study will utilize a cross-sectional cohort study design and will seek to enroll 25 male and female healthy adult participants (18-35 yo). Participants will report to the laboratory for three total sessions (Session 1: informed consent and task familiarization; Session 2: testing; Session 3: knee joint status assessment). The primary outcomes of interest include lower extremity thigh and shank acceleration and velocity data (wearable sensor data), lower extermity 3D kinematics and kinetics (motion capture data), and lower extremity muscle function (EMG data) during walking gait, as well as functional balance and patient-reported subjective outcomes. Data will be analyzed by calculating change scores from the pre- to post-experimental effusion outcome measure testing. Paired-samples t-tests and Cohen's d effect sizes will be used to assess changed in wearable sensor data from pre- to post-experimental effusion. Correlation statistics will be used to determine if there are association between the motion capture and wearable sensor data. The potential risks associated with an experimental joint effusion will be addressed by maintaining appropriate sterile conditions and having the participant check-in with the PI (licensed healthcare provider) at 48 hours following testing session.