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Knee Disease clinical trials

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NCT ID: NCT04821154 Recruiting - Knee Osteoarthritis Clinical Trials

Persona Revision Knee System Outcomes

Start date: June 14, 2021
Phase:
Study type: Observational

The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.

NCT ID: NCT04814082 Recruiting - Knee Osteoarthritis Clinical Trials

Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Patients with degenerative joint disease can effectively be treated with a primary total knee replacement to reduce pain and improve function in their daily lives. Theoretically, achievement of normal knee motion using a medial pivot design in total knee replacements can be recreated in comparison to single radius designs, which could lead to an improvement in post-surgical outcomes and satisfaction with the procedure. The aim of this study is to compare two types of implant designs (medial pivot and single radius) in a total knee replacement using clinical outcomes, patient reported outcomes, and overall function assessed by a specialized gait laboratory.

NCT ID: NCT04785014 Completed - Knee Disease Clinical Trials

Effect of USG-guided Baker's Cyst Aspiration

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

ABSTRACT Objective: The aim of this study was to investigate the effect of ultrasonography (USG)-guided Baker's cyst (BC) aspiration in the treatment of BC. Design: A total of 40 patients presented to our polyclinic with the complaints of swelling at the back of the knee. The 40 patients were randomly divided into two groups: (I) aspiration group (n=20) and (II) control group (n=20). In the aspiration group, BC content was aspirated percutaneously under USG guidance, whereas no aspiration was performed in the control group. Additionally, the participants in both groups were trained on how to perform exercises and were also recommended to practice cold treatment for 15 min both in the morning and evening for 2 weeks. All the patients were followed up with USG at the first and third months, VAS, WOMAC, NHP , Lysholm and Cincinnati. The success of the treatment was demonstrated by the decrease in the width, length and area of the BCs and Lysholm, Cincinnati ,VAS, WOMAC and NHP scores.

NCT ID: NCT04727060 Recruiting - Clinical trials for Total Knee Arthroplasty

Open Label Study to Collect Clinical Data to Document Clinical Performance and Safety in Total Knee Arthroplasty

Start date: December 15, 2011
Phase:
Study type: Observational

The purpose of this study is to evaluate clinical performance and safety in total knee arthroplasty using HLS implants.

NCT ID: NCT04650594 Terminated - Knee Disease Clinical Trials

Functional Outcomes of Knee Protheses for Malignant Tumours of Bone

ISOMUTAR
Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The placement of mega knee prosthesis is a necessity after a large tumor resection and oncological. These mega knee prostheses implanted in the context of oncological surgery have been very few evaluated in the literature. Active knee extension is essential in order to walk properly. The study propose the evaluation of this prosthesis by checking the possibility of locking of the prosthetic joint and thus the possibility of active walking. A more in-depth, isokinetic analysis at 1 year of follow-up will also be done in an exploratory manner, as the literature has no data on this subject.

NCT ID: NCT04648072 Completed - Knee Osteoarthritis Clinical Trials

How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study.

TRUE KnORTH
Start date: November 4, 2020
Phase: N/A
Study type: Interventional

The use of periarticular injection and adductor canal block are well-established techniques used both in combination or in isolation in the management of postoperative pain for patients undergoing total knee arthroplasty. The aim of this study is to investigate whether combining these two techniques have an added benefit, compared to periarticular injection alone, with respect to quality of recovery, functional return, discharge readiness, and short and long term post-operative narcotic use.

NCT ID: NCT04578951 Terminated - Knee Disease Clinical Trials

Measurement of the Quality of Life in Patients Operated With a Total Knee Prosthesis (TKA) From the FHK® Range.

Start date: September 28, 2020
Phase:
Study type: Observational

As part of Medical Devices CE marking regulatory process, an appropriate post-market clinical follow-up (PMCF) is required. This PMCF study is in the framework of CE mark renew of FHK® total knee prosthesis, it aims to answer specific questions related to safety and performance of the device, when used in accordance with the approved instructions for use. This study is based on a quality of life self-assessment from the preoperative to postoperative phases and up to two years of follow-up.

NCT ID: NCT04497129 Recruiting - Knee Osteoarthritis Clinical Trials

ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA)

Start date: August 17, 2020
Phase: N/A
Study type: Interventional

ROMTech is focused on transforming the healthcare market by delivering lower extremity rehabilitation systems that are effective, efficient for patient use, cost-effective, and provide better patient outcomes while simultaneously decreasing rehabilitation and overall recovery times.

NCT ID: NCT04422119 Recruiting - Surgical Wound Clinical Trials

Standard Dressing Versus Moist Dressing in the Course of the Postoperative Wound in Patients With Knee Prosthesis

APOSIT-PTG
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The aim of the study is: to evaluate the efficacy of two post-operative dressings in the management of the surgical wounds in patients who received a knee prosthesis

NCT ID: NCT04388111 Completed - Pain, Acute Clinical Trials

Intraosseous Morphine in Primary TKA

Start date: May 5, 2020
Phase: Phase 4
Study type: Interventional

The research team wants to investigate if an intraosseous injection (directly into the bone marrow) of morphine during primary total knee replacement helps with post-operative pain following primary total knee replacement surgery. For this study patients will either be randomized into one of two groups: Group 1: Receives an intraosseous injection of morphine (mixed with standard antibiotics) during their primary total knee replacement or Group 2: Serves as the control group and only receives an intraosseous injection of antibioitics during their total knee replacement. The research team will have patients fill out a symptom journal for two weeks following their surgery to measure pain levels and pain medication consumed throughout the day as well as nausea and other symptoms. Additionally, the research team will take blood samples both intraoperatively and post-operatively (10 hours post-op) to measure the level of inflammatory markers as well as morphine.