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Knee Disease clinical trials

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NCT ID: NCT06305858 Recruiting - Knee Disease Clinical Trials

Partial Versus Total Knee Replacement in Bicompartmental Gonarthrosis (Medial and Patellofemoral): Prospective Functional Assessment Study

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The study is, in accordance with current legislation, definable as a prospective single-center interventional randomized study. The aim of the study is to evaluate the post-operative recovery of the group A patient undergoing the partial knee replacement surgical procedure compared to the group B patient undergoing the total knee replacement surgical procedure through clinical/functional scores. The primary outcome is evaluate the difference in score of the KSS questionnaire, at 1 month after surgery, completed by the patient of group A compared to the patient of group B. The population consists of 48 adult patients with gonarthrosis divided into two groups: 24 patients Group A experimental group: partial denture surgical procedure 24 patients Group B control group: total denture surgical procedure with patellar resurfacing

NCT ID: NCT06302218 Not yet recruiting - Knee Osteoarthritis Clinical Trials

ESPB vs iPACK+ACB in Total Knee Arthroplasty

Start date: April 1, 2024
Phase: Phase 4
Study type: Interventional

Effect of iPACK block with Adductor Canal Block and ESPB on pain management, and NLR and PLR following knee arthroplasty

NCT ID: NCT06284824 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Comparison of Two Robotic-Assisted Total Knee Arthroplasty Systems

Start date: May 2024
Phase: N/A
Study type: Interventional

The goal of this prospective study is to compare two different knee replacement robots. This study will look at patient reported outcome measures and data collected during the operation. The main questions this study aims to answer include: - Will the patient reported outcomes differ between the two groups? - Will the intraoperative data differ between the two groups? Participants will undergo total knee replacement with one of the two robots, complete standardized surveys, and have x-rays taken.

NCT ID: NCT06203483 Recruiting - Knee Osteoarthritis Clinical Trials

Ultrasound Guıded Adductor Canal Block vs Perıcapsular Nerve Group Block in Knee Artroplasty

Start date: January 20, 2024
Phase: N/A
Study type: Interventional

Knee arthroplasty surgery numbers are increasing depending on joint deformities and cartilage degenerations. Severe postoperative pain may occur in these patients due to surgery and the placed prosthesis. The aim of study is to compare the effectiveness of AKB and PENG block for postoperative analgesia management after knee arthroplasty.

NCT ID: NCT06144099 Not yet recruiting - Prostate Cancer Clinical Trials

Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery

Start date: March 1, 2024
Phase: Phase 4
Study type: Interventional

The primary endpoint of this study is the completion time of hemostasis treatment when administered Fresh frozen plasma (FFP) and frozen powder coagulation factor concentrate (PCC) in goal-directed bleeding management for non-cardiac surgery.

NCT ID: NCT06087562 Active, not recruiting - Knee Osteoarthritis Clinical Trials

iPACK Block for Total Knee Arthroplasty

Start date: June 16, 2020
Phase: Phase 4
Study type: Interventional

This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee arthroplasty.

NCT ID: NCT06084403 Recruiting - Knee Osteoarthritis Clinical Trials

Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy. Selective blockade of the saphenous nerve in the adductor canal provides effective analgesia without quadriceps muscle weakness. It has been shown that the adductor canal block (ACB) block increases the spread of local anesthetics in a distal and proximal way. Therefore, the proximal spread of local anesthetics may cause possible quadriceps weakness. The distal spread of local anesthetics may increase analgesic effect via sciatic nerve. The different volumes for ACB is a topic of discussion. The aim of this study is to compare the different volumes of US-guided ACB performing for postoperative analgesia management after total knee arthroplasty surgery.

NCT ID: NCT05889286 Not yet recruiting - Knee Disease Clinical Trials

F18-MHF: Orthopedic Implants-Associated Infection Detection

Start date: June 2024
Phase:
Study type: Observational

Following intravenous injection of [F-18]MHF as a bolus, dynamic PET imaging of the lower limbs will be acquired for approximately 90 minutes. The acquired images will be processed and viewed on a MIMVista or similar workstation. The uptake pattern of [F-18]MHF around infected orthopedic knee implant will be determined and compared with its uptake pattern around non-infected knee implants. This study will look at how [18F]MHF goes into normal knee replacements and those with suspected infection.

NCT ID: NCT05749965 Not yet recruiting - Knee Disease Clinical Trials

Results of Unicompartmental Knee Arthroplasties in Patients Beyond Historical Indications (PUCIL)

PUCIL
Start date: March 2023
Phase:
Study type: Observational

Primary objective: To compare medial uni compartimental knee arthroplasty between patients who had a limit factor prior to the surgery ans patients who fill thé historical criteria. Secondary objectives 1 to compare survival of medial UKA between patients with one limit factor and those with multiple limits. 2. To identify the prognosis factors of failure in medial UKA in our center during the time of our analysis (2009-2015)

NCT ID: NCT05669066 Completed - Knee Osteoarthritis Clinical Trials

Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement

Start date: July 10, 2017
Phase: N/A
Study type: Interventional

The main purpose of this study is to look at whether meditation techniques can help reduce pain and opioid use after surgery.