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The Comparison Between Ringer Lactate Solution and Normal Saline in Post-Operative Period of Kidney Transplantation — RINNOR  

Kidney Transplant; Complications Clinical Trial

Official title:
The Comparison Between Ringer Lactate Solution and Normal Saline in the First Week Post-Operative Period of Deceased Donor and Living Donor Kidney Transplantation

Clinical Trial Summary

This is a randomized controlled pragmatic clinical trial. We aim to evaluate the effect of Ringer lactate solution (RLS) and normal saline solution (NSS) on the electrolyte abnormality of kidney transplant recipients (KTR) during the first post-operative week. The problem with using NSS as a standard replacement fluid is the hyperchloremic metabolic acidosis which might compromise the kidney allograft function. A total 60 KTR will be enrolled and randomized to receive either RLS or NSS. The primary outcome is serum bicarbonate level at day 5 after transplantation. Secondary outcomes include the serum potassium, serum sodium, serum chloride, cytokine panel, and the incidence of delayed graft function.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06030609
Study type Interventional
Source King Chulalongkorn Memorial Hospital
Contact Suwasin Udomkarnjananun, MD, PhD
Phone +66899679885
Email suwasin.u@gmail.com
Status Not yet recruiting
Phase Phase 3
Start date June 1, 2024
Completion date August 31, 2025
View Details
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