Effects of Graft Vascular Dimensions on Surgical and Functional Outcomes of Living Donor Kidney Transplantation

Kidney Transplant; Complications Clinical Trial

Official title: Effects of Graft Vascular Dimensions on Perioperative Surgical and Functional Outcomes of Living Donor Kidney Transplantation in Pediatrics and Adults: A Prospective Case Series

Status Not yet recruiting

Clinical Trial Summary

1. Correlate the radiological and intraoperative measuring of the vascular dimensions,

2. Assess the effect of the vascular dimensions on the short-term surgical complications and

3. Assess the effect of the vascular dimensions on the primary graft function in pediatric and adults KTs.

Clinical Trial Description

Vascular complications after kidney transplantation (KT) are variably rare with an incidence of 3-15%. They are a significant and most serious part of surgical complications of KT. They may acutely result in graft loss during surgery or early in the perioperative period and may threaten patient's life. The most common forms of early vascular complications are haemorrhage, hematomas, arterial or venous thrombosis, arterial vasospasm, and arterial intimal dissection. In pediatric and adult KT, most studies addressing the vascular complications followed a common attitude of estimating the prevalence and management of these complications rather than studying the predisposing factors. Specifically, studying the normal and abnormal anatomy of the grafts has mainly been directed towards the number of graft vessels. However, there are many other vascular parameters that may potentially influence the outcome of vascular anastomosis and therefore the graft and patient outcomes. To the best of the investigators knowledge, the vascular dimensions of the renal and iliac vessels, such as the length, diameter and site of anastomosis to the iliac vessels have not been studied before so the investigators hypothesis that these dimensions can unequally affect the outcomes of surgery and early graft function in KTs. Hence, this study will be conducted to assess the effects of the vascular dimensions on the outcomes of surgery and primary graft function in pediatric versus adult living donor KT. ;

Related Conditions & MeSH terms

• Kidney Transplant; Complications

• NCT number: NCT05797389
• Study type: Observational
• Source: Assiut University
• Contact: Mohamed L Shehata
• Phone: 00201093590017
• Email: mohamed.l.m.sh@gmail.com
• Status: Not yet recruiting
• Start date: April 2023
• Completion date: April 2025