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Bicarbonate Administration in Kidney Transplant Recipients

Kidney Transplant; Complications Clinical Trial

Official title:
Bicarbonate Administration in Kidney Transplant Recipients

Clinical Trial Summary

Metabolic acidosis is associated with vascular endothelial dysfunction and is a common complication in patients who have received a kidney transplant. Kidney transplant recipients (KTR) with lower serum bicarbonate levels, even within the normal range, have an increased risk of graft loss and mortality. The investigators propose a prospective, double-blind, randomized, placebo-controlled, 18-week crossover pilot study to examine the effects of sodium bicarbonate on vascular endothelial function, graft function, and cognitive function in 20 KTR patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03428464
Study type Interventional
Source University of Colorado, Denver
Contact
Status Completed
Phase N/A
Start date December 5, 2018
Completion date March 25, 2020
View Details
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