Kidney Stone Clinical Trial
Official title:
Comparing the Efficacy of Thulium Fiber Laser vs. Holmium:YAG Laser for the Ureteroscopic Treatment of Patients With Urinary Stone Disease: a Randomized Controlled Trial
This is a randomized controlled trial which aims to compare the efficacy and safety of Thulium fiber laser (TFL) and holmium:yttrium-aluminum-garnet (Ho:YAG) laser ablation during the treatment of upper urinary tract stone disease with flexible ureteroscopy, demonstrating clinical superiority of TFL.
| Status | Recruiting |
| Enrollment | 120 |
| Est. completion date | February 23, 2026 |
| Est. primary completion date | November 23, 2025 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 99 Years |
| Eligibility | Inclusion Criteria: - Renal/ureteral stones > 4 mm Exclusion Criteria: - Anatomical abnormalities |
| Country | Name | City | State |
|---|---|---|---|
| Italy | IRCCS Ospedale San Raffaele | Milan |
| Lead Sponsor | Collaborator |
|---|---|
| IRCCS San Raffaele |
Italy,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Lithotripsy speed | Through study completion, an average of 1 year | ||
| Secondary | Stone free rate | 3 months after the procedure |
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