SNP-based Prediction of Recurrence Risk in Kidney Stone Patients

Kidney Stone Clinical Trial

Official title:

SNP-based Prediction of Recurrence Risk in Kidney Stone Patients: a Prospective Multicenter Observational Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04937192
• Other study ID #: MRER2013-001
• Status: Recruiting
• Start date: January 1, 2012
• Est. completion date: December 31, 2023

Study information

• Verified date: October 2022
• Source: The First Affiliated Hospital of Guangzhou Medical University
• Contact: Guohua Zeng, M.D.
• Phone: 13802916676
• Email: gzgyzgh[@]vip.sina.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence.

Description:

In this study, investigators are prospectively testing whether SNP are associated with kidney stone recurrence. Investigators will test the hypothesis that SNP predispose kidney stone patients to recurrence.

Investigators hope to identify predictors for the kidney stone recurrence. This would allow the identification of a subpopulation of kidney stone patients that would benefit most from prevention measures.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1300
• Est. completion date: December 31, 2023
• Est. primary completion date: December 31, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age 18 or older

• Kidney stone former who the stone was removed completely.

• Ability to give informed consent

Exclusion Criteria:

• Patient refuses or is unable to give consent

Related Conditions & MeSH terms

• Calculi
• Kidney Calculi
• Kidney Stone
• Nephrolithiasis
• Recurrence

Intervention

Other:
• No intervention
No intervention

Locations

Country	Name	City	State
China	The First Affiliated Hospital of Guangzhou Medical University	Guangzhou	Guangdong

Sponsors (18)

Lead Sponsor

Collaborator

The First Affiliated Hospital of Guangzhou Medical University

301 Hospital, Baoshan No.2 People's Hospital, Dehong People's Hospital, Guangdong No.2 People's Hospital, Huizhou Municipal Central Hospital, Jiangmen Central Hospital, People's Hospital of Xinjiang, Second Affiliated Hospital of Guangzhou Medical University, Shenzhen Longgang Central Hospital, Shenzhen People's Hospital, The 2nd.Hospital of Tianjin Medical University, The Second Affiliated Hospital of Kunming Medical University, Wuhan University Renmin Hospital, Xiangya Hospital of Central South University, Yongzhou Center Hospital, Zhongda Hospital Southeast University, ZhuZhou Central Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Stone-free survival	Time to first stone recurrence from stone-free	From date of stone-free until the date of first stone recurrence (up to 7 years)