Clinical Trials Logo

Joint Diseases clinical trials

View clinical trials related to Joint Diseases.

Filter by:

NCT ID: NCT05357378 Recruiting - Osteoarthritis, Hip Clinical Trials

Safety and Effectiveness of the HIT Reverse HRS

Start date: July 15, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the use of the HIT Reverse Hip Replacement System is safe and effective in patients undergoing total hip replacement. We will determine whether it is safe and effective by comparing it to the control devices.

NCT ID: NCT05356650 Recruiting - Clinical trials for SACROILIAC JOINT DYSFUNCTION

Mulligan's Mobilization and Proprioceptive Neuromuscular Facilitation Technique in Sacroiliac Joint Dysfunction

Start date: April 15, 2022
Phase: N/A
Study type: Interventional

This study will aim to compare the effects of mulligan mobilization and PNF on pain and disability with patients of SIJ dysfunction and will be helpful for clinical physiotherapist to choose more effective treatment protocol for patients as there are fewer researches on comparison of these techniques.

NCT ID: NCT05324826 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Effectiveness of Handheld Ultrasound for Diagnosing Patients With TMD

Start date: May 16, 2022
Phase:
Study type: Observational

The aim of this research is to add to the limited body of knowledge comparing the effectiveness of ultrasound (US) to MRI diagnoses in patients with TMJ disorders. More specifically, we will review the efficacy of handheld US devices, which has not yet been done to the author's knowledge.

NCT ID: NCT05319223 Recruiting - Arthropathy Clinical Trials

Patient Blood Management in Orthopedic Surgical Patients in Turkey

PABMOS
Start date: February 1, 2022
Phase:
Study type: Observational

Transfusion practice for surgical patients has changed from replacing surgically lost blood with allogeneic blood transfusions to implementing strategies that reduce transfusion requirements. Patient Blood Management (PBM), which is "the timely application of evidence-based medical and surgical concepts designed to maintain haemoglobin concentration, optimize hemostasis and minimize blood loss in an effort to improve patient outcome. There is mounting evidence that multimodal patient blood management (PBM) programmes can be effective at improving postoperative outcomes and reducing perioperative blood transfusions and costs The Turkish Society of Anaesthesiologists PBM Task Force has been working on this subject and studied transfusion practice throughout all through the peri-operative periods. Unfortunately we documented a high transfusion rate in major surgical patients in Turkey. One of the surgeries, that has high transfusion rate, was orthopaedic surgery. According to our recent data we planned to implement PBM in major orthopaedic surgical patients and evaluate the effects PBM in transfusion rate and patient outcomes. While some elements of PBM have a strong evidence base in hip or knee replacement, such as the use of tranexamic acid (TXA) the evidence for preoperative anaemia optimisation with iron is less robust. Implementing PBM all through the operative period gains more importance.

NCT ID: NCT05305833 Recruiting - Clinical trials for Temporomandibular Disorder

Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease

Start date: October 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

It will be evaluate the safety of mesenchymal stem cells and adipose tissue derived stromal vascular fraction (SVF) in temporomandibular joint disease cases.

NCT ID: NCT05295004 Recruiting - Sleep Disturbance Clinical Trials

The Effect of Mindfulness Training Before Primary Total Joint Arthroplasty on Sleep Quality

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

The primary purpose of this study is the determine whether a 15 minute Mindfulness Meditation (MM) administered at the preoperative appointment prior to primary unilateral total joint arthroplasty (TJA) results in any improvement in Pittsburg Sleep Quality Index (PSQI) score, a validated metric for sleep quality, at 2, 6 or 12 weeks post-operatively.

NCT ID: NCT05292339 Recruiting - Osteoarthritis Clinical Trials

Ketorolac in Upper Extremity Tendinopathy and Arthropathy

Start date: January 31, 2023
Phase: Phase 4
Study type: Interventional

Osteoarthritis (OA) and inflammatory conditions of the tendons and joints of the shoulder, elbow, hand, and wrist are common yet disabling diseases. Standard management utilizes conservative measures to minimize pain and improve function. Conservative pharmacological management commonly includes corticosteroid and ketorolac injections which have been well investigated as a modality of pain control and improved function in large joint OA. However, fewer studies yielding mixed results on the duration of symptomatic relief exist for arthropathy and tendinopathy of these joints. The goal of this study is to evaluate the efficacy of ketorolac and triamcinolone injections for common shoulder, elbow, wrist, and hand tendinopathy or arthropathy. Participants will be blinded to the treatment received. The duration of an individual participant's participation in this study is 24 weeks. During this time period, patients will be asked to return to the clinic for an in-person follow-up 6 weeks after the injection with either ketorolac or triamcinolone) in order to assess participants' outcomes. All work related to this project will take place at the Emory Sports Medicine Complex, Emory Executive Park, Emory Musculoskeletal Institute, the Emory University Orthopaedic and Spine Hospital, and the Emory Saint Joseph's Hospital. This study will add to existing knowledge by providing further insight into how wrist arthropathy should be most optimally and conservatively managed.

NCT ID: NCT05227924 Recruiting - Clinical trials for Femoral Neck Fractures

Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty

Start date: September 15, 2021
Phase:
Study type: Observational

The purpose of this post-market clinical follow up study is to assess the safety and effectiveness of the SYMBOL range of medical devices. The study will evaluate the outcome of Total Hip Arthroplasty using medical devices from SYMBOL range over a period of 10 years.

NCT ID: NCT05187936 Recruiting - Hemophilia A Clinical Trials

Pre-clinical Models for Mesenchymal Stem Cell Therapy in Hemophilic Arthropathy

Start date: October 1, 2021
Phase:
Study type: Observational

Hemophilia is a constitutional coagulation disorder responsible for a hemorrhagic phenotype in patients from an early age. Hemarthrosis is one of the most frequent complications in hemophiliacs and leads to the development of severe and early arthropathy, sometimes as early as childhood. To date, there is no curative treatment for these joint disorders and preventive treatments are insufficient to completely prevent joint degradation. Mesenchymal stem cells have been shown to be of therapeutic interest in the management of pathologies such as osteoarthritis and inflammatory arthritis through their anti-inflammatory, regenerative and anti-apoptotic effects. Hemophilic arthropathy is a separate condition at the border of these two diseases Our study aim to show pre-clinical interest of mesenchymal stem cell therapy in hemophilic arthropathy

NCT ID: NCT05149729 Recruiting - Hip Arthropathy Clinical Trials

Mid-Term Natural Course Postoperative of Crowe Type III-IV Hip Dysplasia

Start date: February 10, 2021
Phase: N/A
Study type: Interventional

Comparison of preoperative and postoperative mid-term course of patients with Crowe Type 3 and Type 4 hip dysplasia.