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Joint Diseases clinical trials

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NCT ID: NCT04449146 Recruiting - Clinical trials for Shoulder Osteoarthritis

Scapular Positioning in Standing Position Using Sonography

3S
Start date: August 31, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to analyse the positioning of the scapula in standing position and compared to the supine position (CT scan) in 3 dimensions (3 rotations of the scapula) using a non-radiant, portable system, combining an ultrasound probe with marker and a camera integrated into a Tablet for the three-dimensional location of the marker (probe).

NCT ID: NCT04438265 Recruiting - Hip Arthropathy Clinical Trials

Quadratus Lumborum Type 2 as Chronic Hip Pain Treatment

Start date: September 1, 2020
Phase:
Study type: Observational

The main objective of the study is to assess whether the performance of type 2 quadratus lumborum block produces an improvement in the quality of life of the patient with osteoarthritis of the hip.

NCT ID: NCT04435951 Completed - Clinical trials for Temporomandibular Joint Dysfunction

The Effect Of Temporomandibular Joint Dysfunction On Pain, Quality Of Life And Psychological Status

Start date: March 6, 2017
Phase:
Study type: Observational

The aim of this study was to investigate the effects of temporomandibular joint dysfunction (TMJD) on pain, quality of life and psychological status. A total of one hundred twenty people participated in the study, sixty with TMJD symptoms (according to the Research Diagnostic Criteria for Temporomandibular Disorders) and sixty without TMJD symptoms. The severity of temporomandibular joint (TMJ) pain and headache was assessed using a visual analog scale (VAS), pain threshold using an algometer, anxiety and depression levels with the Hospital Anxiety and Depression Scale (HADS), and the quality of life level was assessed by Short Form-36 (SF-36). Treatment of TMJD with appropriate therapies and psychological support techniques may reduce TMJD symptoms and improve patients' quality of life and psychological status.

NCT ID: NCT04419116 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Clinical Outcomes Between Tibial Preservation Bone Cut and Conventional Tibial Bone Cut Following Medial UKA

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The mobile bearing unicompartmental knee arthroplasty has shown excellent clinical outcome and survivorship. However, some studies have shown that the patients still had medial knee pain and shown worst the clinical outcome, even though the survivorship was excellent. The medial knee pain after operation was the one cause of revision. The incidence of medial knee pain was 0%-9%. The cause of medial knee pain was overloading on the medial plateau, local inflammation, over hanging of the tibial component and overstretching of the MCL due to the application of excessive polyethylene. Therefore, the tibia in this study was cut with under resection technique for reducing the overloading on the medial tibial plateau. The purpose of this study is to compare medial knee pain between tibial bone cut preservation technique and conventional tibial bone cut technique following mobile bearing UKA.

NCT ID: NCT04415931 Completed - Clinical trials for Shoulder Osteoarthritis

Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty

Start date: August 15, 2020
Phase: N/A
Study type: Interventional

Pain management following total shoulder arthroplasty is an important factor in determining patient outcomes and satisfaction. Interscalene brachial plexus blockade has been used successfully to minimize pain in the acute post-operative period. While shown to be effective, interscalene blockade has known complications. In addition, interscalene block has been shown to be significantly more expensive when compared to local anesthesia infiltration. Local anesthetics such as bupivacaine have long been used to assist in post-operative anesthesia. Recent reports have demonstrated local infiltration of liposomal bupivacaine to be similar to interscalene block in regards to patient analgesia even in the first 24 hours post operatively, with the added benefit of lower complications and costs. While most reports examine the efficacy of local infiltration with liposomal bupivacaine in the shoulder, other total joint literature has been positive regarding the use of local infiltration analgesic mixture for improved post-operative analgesia using a multi-modal approach to infiltrative analgesia. Despite these reports, the role and efficacy of local infiltration analgesia in shoulder arthroplasty is lacking. The purpose of the proposed study is to determine the efficacy and safety of local infiltration analgesia in shoulder arthroplasty in comparison to interscalene block through a randomized prospective clinical trial. Our hypothesis is that local infiltration analgesia will lead to postoperative pain scores, opiate consumption, and complication rate that are not significantly different from interscalene block.

NCT ID: NCT04410731 Active, not recruiting - Clinical trials for Facet-Mediated Low Back Pain

Allogeneic BM-MSCs in Patients With Lumbar Facet Arthropathy

Cellkine
Start date: April 28, 2020
Phase: Phase 1
Study type: Interventional

Researchers are conducting this study to learn more about the side effects of bone marrow-derived stem cells when injected into the facet joints for the treatment of painful lumbar facet joint arthropathies.

NCT ID: NCT04406519 Completed - Hemophilia Clinical Trials

Evaluation of Static Postural Balance in Children With Hemophilia and Its Relationship With Joint Health

Start date: February 1, 2018
Phase:
Study type: Observational [Patient Registry]

Hemophilia is a rare hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX.Bleeding disorders mainly affect the musculoskeletal system. Intra-articular bleeding is an important complication related to hemophilia and usually occurs in large synovial joints such as knees and ankles. Initially, these bleeds occur non-specific spontaneously and usually affect one joint, and repeated bleeding makes that joint a target joint. Postural balance can be defined as the ability to maintain a stable posture for maximum duration with minimal body sway, or to hold the body centre of gravity (CoG) over its base support in varying conditions (1). Somatosensorial information from mechanoreceptors, visual and vestibular receptors is required to maintain postural balance. Postural balance is tried to be controlled by the postural adjustments provided by the contraction of the lower limb muscles and trunk muscles before perturbation. Spontaneous hemarthrosis is a distinctive feature of severe haemophilia, and that recurrent bleedings may likely to cause postural balance disorders by disrupting proprioceptive inputs from mechanoreceptors in the joint. Data on how bleeding affects postural balance in children with hemophilia is unclear.In the relationship between the clinical evaluation of hemophilia and postural balance, there is little research in the literature.

NCT ID: NCT04405947 Completed - Clinical trials for Rotator Cuff Arthropathy

Influenze of Approach in Reversed Shoulder Prosthesis

Start date: January 13, 2016
Phase: N/A
Study type: Interventional

To determine the differences in the placement of the glenoid implant of the inverted prostheses when they are implanted using a superior approach and using an anterior approach.

NCT ID: NCT04399928 Completed - Clinical trials for Degenerative Joint Disease

EU Safety and Efficacy Study Regarding the R3 Acetabular Hip System

Start date: May 18, 2009
Phase:
Study type: Observational

The objective of this study is to determine the long-term safety and effectiveness from the R3 Acetabular Hip System. The study hypothesis is that implant survivorship of the R3 cup is at least 97% at 3 years, 95% at 5 years, 93% at 7 years, and 90% at 10 years follow-up.

NCT ID: NCT04376333 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Individualized Assessment and Treatment for TMD

TMD3c
Start date: February 3, 2021
Phase: N/A
Study type: Interventional

Temporomandibular/orofacial pain disorders (TMD) are a group of painful conditions with multiple determinants.This proposal has two main goals: 1) to test a highly individualized, adaptive treatment for TMD that has potential to be more effective than other psychosocial treatments; and 2) to discover the mechanisms by which psychosocial treatments work in chronic pain. TMD patients (N=160) will be randomized to receive standard care (STD) + an individualized assessment and treatment program (IATP) or to standard care + conventional cognitive-behavioral treatment (STD+CBT). It is expected that the STD+IATP treatment will yield lower pain, depression and interference scores over time than STD+CBT, and that changes in coping ability will mediate the treatment effects on outcomes.