Clinical Trials Logo

Joint Diseases clinical trials

View clinical trials related to Joint Diseases.

Filter by:

NCT ID: NCT04524806 Completed - Clinical trials for Temporomandibular Disorder

Influence of Stabilization Splint Thickness on The Temporomandibular Disorders

Start date: July 1, 2013
Phase: N/A
Study type: Interventional

The aim of the study is assessing the effect of the stabilization splint (SS) thickness on the temporomandibular disorder's and their symptoms; such as muscle or temporomandibular joint (TMJ) pain, TMJ sounds, and limitation of mouth opening.

NCT ID: NCT04524312 Completed - Surgery Clinical Trials

Dynamic Congruence Total Knee Replacement vs Posterior-stabilized

K-Mod
Start date: December 1, 2017
Phase: N/A
Study type: Interventional

This study compares and evaluates differences in movement analysis, patient-reported outcome between patients undergoing total knee arthroplasty with use of either Zimmer Biomet NexGen with posterior stabilization and Bioimplanti K-Mod cruciate-retaining with dynamic congruence

NCT ID: NCT04514731 Recruiting - Arthropathy of Knee Clinical Trials

Magnesium Sulfate and Neuroendocrine Hormone

Start date: January 21, 2021
Phase: Phase 4
Study type: Interventional

Total knee arthroplasty is a procedure that relieves pain in patients with severe symptomatic osteoarthritis, but it can be associated with postoperative pain, which hinders recovery. In the previous study, we reported evidence of increased pain in patients undergoing staged total knee arthroplasty, in whom the second operated knee had greater sensitivity (tertiary hyperalgesia) as a result of the surgical injury to the first operated knee. Magnesium sulfate is an effective analgesic adjuvant for postoperative pain. Its analgesic property seems to be associated with the regulation of calcium influx into the cells, or antagonism of N-methyl-D-aspartate receptors in the central nervous system. Additionally, magnesium is known to have an anti-inflammatory effect. Inflammatory state may accompany with pain via peripheral or central sensitization. Recently, we reported that magnesium sulfate effectively attenuates not only postoperative pain but also increased pain intensity without serious adverse effects in the bilateral staged total knee arthroplasty. However, the exact mechanism regarding these effects of magnesium sulfate remains unclear. In the present study, we will investigate the analgesic mechanism of magnesium sulfate via analysis of endocrine neurosteroid levels in patients undergoing bilateral staged total knee arthroplasty.

NCT ID: NCT04491318 Completed - Clinical trials for Hemophilia Arthropathy

COVID-19 Quarantine on Musculoskeletal Status in Hemophilia

HemoCov
Start date: July 1, 2020
Phase:
Study type: Observational

Background. The recurrence of hemarthrosis in patients with congenital coagulopathies favors the development of a progressive, degenerative and intra-articular lesion (hemophilic arthropathy) that mainly affects the knees, ankles and elbows. Pain is one of the main clinical manifestations of hemophilic arthropathy. As a consequence of the COVID-19 pandemic, the Government of Spain, among others, established a total confinement for two months, in order to avoid contagion of the population Objective. To assess the effect of COVID-19 confinement on bleeding frequency, pain perception, and range of motion in patients with hemophilic arthropathy. Study design. Prospective observational study. Method. 27 patients with hemophilia A and B will be included in this study. Patients will be recruited from the Spanish Hemophilia Federation (Fishemo) specialized center for hemophilia patients. The dependent variables will be: the frequency of bleeding (through a self-report), the perception of pain (measured with the visual analog scale and a pressure algometer), the joint state (with the Hemophilia Joint Health Score), and the range of joint movement (measured with a goniometer). Two evaluations will be carried out: pre-treatment (carried out in the month of February, as a periodic evaluation) and post-treatment (at the end of the period of confinement in Spain). Expected results. The aim is to observe the sequelae caused by confinement and a sedentary lifestyle in patients with hemophilic arthropathy, through changes in joint status, pain and range of motion.

NCT ID: NCT04481711 Completed - Orthopedic Disorder Clinical Trials

Total Knee Arthroplasty and Clinical Findings

Start date: November 8, 2018
Phase: N/A
Study type: Interventional

Knee osteoarthritis is a common disease that causes pain and loss of function. Total Knee Arthroplasty (TKA) is a frequently used surgical method in the treatment of severe knee osteoarthritis. The aim of this study was to investigate the effect of TKA on IL-6, TNF-α and IL-1β cytokine levels, pain intensity at rest and walking, knee joint valgity angle,malaligment, functional status and knee joint position sense.

NCT ID: NCT04477122 Completed - Clinical trials for Temporomandibular Joint Disorders

Effects of Radial Shock Wave Therapy in the Treatment of Temporomandibular Joint Syndrome.

Start date: October 27, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess the effects of radial shock wave therapy in the treatment of temporomandibular joint syndrome. For this objective, subjects recruited will be allocated in an experimental group or a placebo group. Both groups will receive one manual therapy and radial shock waves therapy (real for experimental group, a sham device for placebo group) session per week along one month. Pain, neck function and quality of life measured will be performed before the intervention, after the last treatment and at one month follow-up.

NCT ID: NCT04469088 Completed - Clinical trials for Temporomandibular Joint Disorders

Effectiveness of Dry Needling vs Manual Therapy in Patients With Temporomandibular Joint Disorders.

Start date: August 11, 2020
Phase: N/A
Study type: Interventional

Temporomandibular Joint Disorders (TJD) represent a set of conditions that involve pain and dysfunction of the temporomandibular joint. TJD are a frequent disability affection in the worldwide population and the 35% of affected present at least a symptom such as orofacial pain, mouth movement limitations and snapping or crying temporo-mandibular. Due to the increase of the incidence of the TJD the investigators propose to complete this study. A randomized controlled trial with parallel groups have been designed and blind evaluation of the response variable. The hypothesis is that dry needling produces a positive effect in the involved variables of this study in comparison with manual therapy. The aim of this RCT is to compare the effectiviness of the application of manual therapy in comparison with dry needling in the perceived pain, mouth opening, the degree of cervical disability and the pressure-pain threshold (PPT) of myofascial trigger points (MTrP) in patiens with TJD.

NCT ID: NCT04468464 Active, not recruiting - Clinical trials for Temporomandibular Disorders, Articular Disc Disorder (Reducing or Non-Reducing)

Quantitative Evaluation of Osteopathic Treatment in Temporomandibular Joint Disorders Using Magnetic Resonance Imaging

TMD
Start date: September 15, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to assess the impact of osteopathic manual treatment in patients with an anterior disc displacement over sleep and health quality, pain scores and the movement of the condyle and disc of the temporomandibular joint (TMJ) quantitatively.

NCT ID: NCT04457362 Completed - Wrist Arthropathy Clinical Trials

Wrist Arthroscopy Study

Start date: October 10, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the diagnostic efficacy of Arthrex NanoScope compared to conventional arthroscopic instruments. Patients with wrist pathology who are indicated for an arthroscopic procedure will be enrolled pre-operatively after a thorough discussion of the study aims, risks, and benefits. At the time of surgery, under standard conditions, using standard wrist arthroscopy portals, a diagnostic arthroscopy will be performed with the Arthrex Nanoscope. The diagnostic arthroscopy will be performed in a stepwise manner for consistency with notation of pathology and intended intervention. The diagnostic arthroscopy will then be performed with the standard arthroscopic equipment, again noting pathology and final intervention. Post-operatively, diagnostic accuracy, incidence of change in intervention, and surgeon rated ease of use and confidence will be determined.

NCT ID: NCT04452110 Completed - Device Reliability Clinical Trials

Investigation of the Reliability of Ultrasonography Usage in the Diagnosis of Temporomandibular Joint Diseases

Start date: November 21, 2019
Phase:
Study type: Observational [Patient Registry]

In the literature, temporomandibular joint diseases on the diagnostic value of the use of ultrasonography in diagnosis studies are lacking. In this study in the diagnosis of temporomandibular joint diseases revealing the reliability of the use of ultrasonography. It is aimed to contribute to the literature in terms of.