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Joint Diseases clinical trials

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NCT ID: NCT04582851 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Prevalence of Temporomandibular Joint Disorders Among Egyptian University Postgraduate Students

Start date: December 1, 2020
Phase:
Study type: Observational

The study will take place in Egypt. Postgraduate students from different faculties of the Egyptian Universities will participate. The study will begin in Decemberr 2020.

NCT ID: NCT04580225 Recruiting - Arthritis Clinical Trials

Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE)

PARTE
Start date: January 7, 2021
Phase: N/A
Study type: Interventional

This randomized clinical trial (RCT) aims to compare clinical and radiographic outcomes of different partial wrist fusion techniques in participants with post-traumatic wrist arthritis. Participants with stage II or III scapholunate advanced collapse (SLAC) or scaphoid nonunion advanced collapse (SNAC) who meet the eligibility criteria will be randomly assigned to one of two parallel groups: Group A (partial wrist arthrodesis without triquetral excision i.e. four-corner arthrodesis), or Group B (partial wrist arthrodesis with triquetral excision i.e. three-corner or capitolunate arthrodesis with triquetral excision). The results of this study will provide evidence to guide surgeons in determining the ideal wrist fusion technique in the management of patients with post-traumatic wrist arthritis requiring surgery.

NCT ID: NCT04574479 Completed - Arthropathy of Hip Clinical Trials

Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Management in Total Hip Arthroplasty by Posterior Approach

Start date: December 16, 2020
Phase: Phase 4
Study type: Interventional

Find the impact of supra-inguinal fascia iliaca compartment block on postoperative pain management after total hip arthroplasty by posterior surgical approach

NCT ID: NCT04559295 Active, not recruiting - Low Back Pain Clinical Trials

Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs

Start date: November 21, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

Intradiscal delivery of bone marrow concentrate (BMC) into discs, facet, epidural space, and sacroiliac joints

NCT ID: NCT04557878 Completed - Clinical trials for Temporomandibular Disorder

Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction

Start date: October 6, 2020
Phase: Phase 2
Study type: Interventional

Purpose of the study is to compare clinically, radiographically and biochemically the effect of intra- articular injection of hypertonic dextrose with a stabilization appliance and the intra- articular injection of 2 ml of liquid phase concentrated growth factor with a stabilization appliance as a prolotherapy for temporomandibular joint anterior disc displacement without reduction.

NCT ID: NCT04555083 Completed - Clinical trials for Sacroiliac Joint Dysfunction

Association Between Chronic Ankle Instability and Sacroiliac Joint Dysfunction

Start date: January 3, 2020
Phase:
Study type: Observational

chronic ankle instability previously approved in many studies that it may lead to more proximal adaptations and negative long term consequences. one of those studies reported, ankle instability patients has hamstring muscle shortening in comparison with non sprained subjects. another one concluded that gluteus maximums muscle has delayed activation and weakness in CAI patients. Both muscles (hamstring and gluteus Maximus ) contribute to sacroiliac joint stability. therefore, this study asked a novel research question, was sacroiliac joint dysfunction (SIJD) associated with CAI?

NCT ID: NCT04549402 Recruiting - Haemophilia Clinical Trials

Movement Visualization in Pain Management in Patients With Hemophilic Arthropathy.

HeMirror
Start date: August 31, 2021
Phase: N/A
Study type: Interventional

Background. The recurrence of hemarthrosis in patients with hemophilia favors the development of a progressive, degenerative intra-articular lesion (hemophilic arthropathy). Pain is one of the main clinical manifestations of this arthropathy. Objective. Assess the safety and efficacy of a pain intervention by visualizing movement using an augmented reality mobile application and immersive 360º video, regarding the frequency of bleeding and the improvement in pain perception and quality of life, joint condition , strength and functionality in patients with hemophilic arthropathy. Study design. Randomized, multicenter, single-blind clinical study. Method. 70 patients with hemophilia A and B will be recruited in this study. The patients will be recruited in 5 regions of Spain. The 8 dependent variables will be: frequency of bleeding (self-registration), pain (measured with the visual analog scale and pressure algometer, Tampa Scale of Kinesiophobia and Pain Catastrophizing Scale), quality of life (SF-12 scale), anxiety (questionnaire of Anxiety Status-Trait-STAI), joint status (Hemophilia Joint Health Score scale), muscle strength (dynamometer) and functionality (6-Minutes Walking test, Quick Disabilities of the arm, shoulder and hand). Three evaluations will be carried out: pre-treatment, post-treatment and after a follow-up period of 6 months. Expected results. To observe the efficacy of the visualization of movement in the characteristics of pain, and its implication in the functionality, joint state, muscular strength and the perception of quality of life in patients with hemophilic arthropathy.

NCT ID: NCT04540809 Completed - Psoriatic Arthritis Clinical Trials

The Effect of Psoriatic Arthritis on the Functions of the Hand

Start date: April 15, 2019
Phase:
Study type: Observational

This study was planned to evaluate the effect of psoriatic arthritis on the strength, proprioception, skill, coordination, and functional condition of the hand and to determine the correlate disease activity with these parameters.

NCT ID: NCT04536103 Recruiting - Osteoarthritis Clinical Trials

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

MVMS_MRI
Start date: April 1, 2022
Phase:
Study type: Observational

Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. MR T1ρ and T2 relaxation times have shown to be promising imaging biomarkers for early cartilage degeneration and prediction of disease progression. However, many challenges remain to clinically applying these techniques, including lack of standardized acquisition and quantification methods, and long acquisition times. The study aims to develop novel, fast and reproducible MR T1ρ and T2 relaxation time imaging methods on MR systems from multiple vendors and establish a platform for standardization and cross validation of these measures as a tool for clinical trials using such techniques. Following method validation, patients at risk for osteoarthritis will be tested.

NCT ID: NCT04535180 Completed - Sarcopenia Clinical Trials

Sarcopenia and Osteoporosis in the Patients With Hemophilia

Start date: January 1, 2019
Phase:
Study type: Observational

Hemophilia is a bleeding disorder and repeated joint bleeding leads to hemophilic arthropathy. Among patients with hemophilia, vitamin D deficiency and hemophilic arthropathy have been associated with osteoporosis in several clinical studies.There is no data on the prevalence of osteoporosis in hemophilia patients in Taiwan or Asia. To the best of our knowledge, no previous studies have reported the prevalence of sarcopenia and correlation with osteoporosis in hemophilia adult patients. This study will investigate the prevalence and corelation of sarcopenia and low BMD in patients with hemophilia. patients in Taiwan. The study will estimate the prevalence of sarcopenia and body composition in the hemophilia population and compared baseline demographic and clinical characteristics between the non-sarcopenia and sarcopenia individuals, with particular emphasis on the overlap with osteoporosis and hemophilic arthropathy.