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Analysing the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke

Ischemic Stroke Clinical Trial

Official title:
Analysing the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke(AXAIS): A Multicenter, Randomized, Open-label, Controlled Trial

Clinical Trial Summary

The main purpose of this trial is to analyse the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke by Metabonomics, proteomics and clinical parameters.

Clinical Trial Description

Xingnaojing is widely used in China, but there is lack of sufficient and reasonable explanation of its intervention effects for acute ischemic stroke currently. The primary hypothesis of this trial is that , Compared with the blank control group, Xingnaojing will produce serial changes in plasma and urine metabolites and biomarkers at baseline (pre-dose), 8 days and 11days . The serial changes may be the potential support to explain the intervention effect of Xingnaojing. All participants will have a National Institutes of Health Stroke Scale(NIHSS)entry score of 4-25. Participants who have planned or already received the intravenous thrombolysis or endovascular treatment will be excluded. The primary outcome will be determined at 11 days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04813445
Study type Interventional
Source Dongzhimen Hospital, Beijing
Contact
Status Recruiting
Phase N/A
Start date May 28, 2021
Completion date September 28, 2022
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