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Study for the Use of Alteplase in Patients Who Awaken With Stroke — AWOKE  

Ischemic Stroke Clinical Trial

Official title:
Alteplase for Waking Onset STROKE

Clinical Trial Summary

This is a pilot study of thrombolytic therapy in patients with ischemic stroke who present with stroke symptoms upon awakening.

Clinical Trial Description

Patients with ischemic stroke are currently only eligible for the treatment with intravenous thrombolysis if the stroke is diagnosed within 4.5 hours from known onset of symptoms.

Many patients awaken with stroke and are excluded from this therapy, following current guidelines.

Patients who suffer from a stroke just before or after waking up may be candidates for thrombolysis and our study will use advanced neuroimaging to select those patients. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01150266
Study type Interventional
Source University of California, San Diego
Contact
Status Withdrawn
Phase Phase 1
Start date August 2011
View Details
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