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NCT00867581 Clinical Trial

Magnetic Resonance Imaging (MRI) Study of the Hippocampus After Infarction in the Territory of the Middle Cerebral Artery

Ischemic Stroke Clinical Trial

Official title:
To Observe Delayed Neuronal Death of Hippocampus After Middle Cerebral Artery Infarction Through Magnetic Resonance Imaging(MRI) Volume Measurement and Magnetic Resonance Spectroscopy(MRS) Study of Hippocampus

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00867581
Other study ID # 30725019-2
Secondary ID
Status Recruiting
Phase N/A
First received March 23, 2009
Last updated March 23, 2009
Start date September 2008

Study information
Verified date March 2009
Source Huazhong University of Science and Technology
Contact Wei Wang, Doctor
Phone 86-027-8366-3648
Email wwang_tjh@126.com
Is FDA regulated No
Health authority China: Ethics Committee
Study type Observational

Clinical Trial Summary

The purpose of this study is to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Description:

40 patients with middle cerebral artery infarction and 40 healthy volunteers will be observed. All of them will receive MRI scan and the assessment of the neuropsychological function (MMSE, AVLT, HAMD) intending to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Recruitment information / eligibility
Status Recruiting
Enrollment 80
Est. completion date
Est. primary completion date July 2009
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Clinical diagnosis of middle cerebral artery infarction

- At least six months from the stroke

- Must be able to measure his(her) neuropsychologic function (by MMSE, AVLT)

Exclusion Criteria:

- Unable to undergo examinations due to disturbances of consciousness or medical conditions

- Severe dementia, apraxia, disturbances of sensation or perception

- Serious complications including severe heart failure, hepatic dysfunction, renal insufficiency,or shock

- Parkinson's disease, malignant tumor, autoimmune diseases

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
China Department of Neurology of Tongji Hospital, Huazhong University of Science and Technology Wuhan Hubei

Sponsors (1)
Lead Sponsor Collaborator
Huazhong University of Science and Technology

Country where clinical trial is conducted

China, 

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