Ischemic Heart Disease Clinical Trial
Official title:
Risk Prediction in Type II Diabetics With Ischemic Heart Disease by Cardiac Autonomic Function
The purpose of this study is to test whether cardiac autonomic dysfunction predicts is a prognostic marker in type-2 diabetics with ischemic heart disease
In patients with type 2-diabetes and ischemic heart disease autonomic function might be
seriously affected.
In the present study, markers of cardiac autonomic dysfunction, repolarization and
respiration abnormalities will be assessed from Holter recordings and 30-minute recordings
of high-resolution three dimensional ECG, non-invasive arterial blood pressure and
respiratory activity.
The correlation between markers of cardiac autonomic dysfunction and markers of severity of
type-2 diabetes will be assessed. Autonomic dysfunction is assumed present when both heart
rate turbulence and deceleration capacity are abnormal ("severe autonomic failure").
Assessment of severity of diabetes includes levels of HbA1c and urine albumine, duration and
treatment of diabetes, and diabetes related complications (nephropathy, neuropathy,
retinopathy).
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Observational Model: Cohort, Time Perspective: Prospective
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