Ischemic Heart Disease Clinical Trial
Official title:
Prevalence and Outcome of Brachial Artery Endothelial Function in Morbidly Obese Patients Undergoing Bariatric Surgery
The relation between obesity and ischemic heart disease (IHD) is under considerable debate.
The reduction in all-cause mortality and, more specifically, the reduction in
cardiac-related mortality seen after weight-loss surgery, may be due to regression or
slowing developement of subclinical IHD. Function of cells lining the arteries (endothelium)
is closely related to the state of IHD and its measurement can serve as a surrogate marker
for the existence and severity of IHD. The investigators hypothesize that the prevalence of
undiagnosed IHD in the morbidly obese population is high and that following surgery for
weight reduction there is a halt in the progression, or even a regression in its severity.
The study includes measurement of endothelial function before and after weight-reducing
surgery.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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