Depression Clinical Trial
Official title:
The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression: a Randomized Controlled Trial
The aim of this trial is to investigate the effects of a single bout of aerobic exercise on sleep in patients with depression.
PRIMARY OBJECTIVE:
The primary objective of this study is to evaluate whether a single bout of aerobic exercise
improves sleep efficiency more than a control condition in patients with depression.
SECONDARY OBJECTIVES:
Secondary objectives are to assess the effects of a single bout of aerobic exercise on 1)
sleep continuity, 2) sleep architecture, 3) pre-sleep arousal, 4) subjective sleep quality,
5) daytime sleepiness, 6) nocturnal blood pressure, 7) heart rate variability, and 8) the
frequency and severity of adverse events.
DESIGN:
This will be a two-arm parallel group, randomized, outcome assessor blinded, controlled,
superiority trial. According to sample size calculation a total of 92 patients will be
randomized using minimization. The trial will take place in the first five days of the
patients' psychosomatic in-patient rehabilitation in the clinic OBERWAID, St.Gallen,
Switzerland. The study visits are scheduled is as follows:
Day 0-2: Screening, inclusion, and graded exercise test to determine exercise intensity of
intervention
Day 3: Questionnaires for background information
Night 1 (day 3-4): Baseline polysomnography and sleep related questionnaires
Day 4: Randomized allocation (control or exercise condition) and performing corresponding
intervention
Night 2 (day 4-5): Follow-up polysomnography and sleep related questionnaires
Day 5: Daytime sleepiness questionnaire
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT05777044 -
The Effect of Hatha Yoga on Mental Health
|
N/A | |
| Recruiting |
NCT04977232 -
Adjunctive Game Intervention for Anhedonia in MDD Patients
|
N/A | |
| Recruiting |
NCT04680611 -
Severe Asthma, MepolizumaB and Affect: SAMBA Study
|
||
| Recruiting |
NCT04043052 -
Mobile Technologies and Post-stroke Depression
|
N/A | |
| Completed |
NCT04512768 -
Treating Comorbid Insomnia in Transdiagnostic Internet-Delivered Cognitive Behaviour Therapy
|
N/A | |
| Recruiting |
NCT03207828 -
Testing Interventions for Patients With Fibromyalgia and Depression
|
N/A | |
| Completed |
NCT04617015 -
Defining and Treating Depression-related Asthma
|
Early Phase 1 | |
| Recruiting |
NCT06011681 -
The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over
|
||
| Completed |
NCT04476446 -
An Expanded Access Protocol for Esketamine Treatment in Participants With Treatment Resistant Depression (TRD) Who do Not Have Other Treatment Alternatives
|
Phase 3 | |
| Recruiting |
NCT02783430 -
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
|
Phase 2/Phase 3 | |
| Recruiting |
NCT05563805 -
Exploring Virtual Reality Adventure Training Exergaming
|
N/A | |
| Completed |
NCT04598165 -
Mobile WACh NEO: Mobile Solutions for Neonatal Health and Maternal Support
|
N/A | |
| Completed |
NCT03457714 -
Guided Internet Delivered Cognitive-Behaviour Therapy for Persons With Spinal Cord Injury: A Feasibility Trial
|
||
| Recruiting |
NCT05956912 -
Implementing Group Metacognitive Therapy in Cardiac Rehabilitation Services (PATHWAY-Beacons)
|
||
| Completed |
NCT05588622 -
Meru Health Program for Cancer Patients With Depression and Anxiety
|
N/A | |
| Recruiting |
NCT05234476 -
Behavioral Activation Plus Savoring for University Students
|
N/A | |
| Active, not recruiting |
NCT05006976 -
A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study
|
N/A | |
| Enrolling by invitation |
NCT03276585 -
Night in Japan Home Sleep Monitoring Study
|
||
| Terminated |
NCT03275571 -
HIV, Computerized Depression Therapy & Cognition
|
N/A | |
| Completed |
NCT03167372 -
Pilot Comparison of N-of-1 Trials of Light Therapy
|
N/A |