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Insomnia clinical trials

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NCT ID: NCT04719143 Completed - Depression Clinical Trials

Effects of Insomnia Treatment on Metabolism in Patients With Depression

Start date: December 20, 2018
Phase: N/A
Study type: Interventional

This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.

NCT ID: NCT04712604 Completed - Insomnia Clinical Trials

Feasibility and Acceptability Study of My Sleep Our Sleep (MSOS) Program

Start date: March 14, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to test feasibility and acceptability of a psycho-behavioral intervention on sleep in cancer patients and their partners.

NCT ID: NCT04706091 Completed - Insomnia Clinical Trials

Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia

Start date: August 12, 2021
Phase: Phase 4
Study type: Interventional

The investigators aim to determine the effect of suvorexant on actigraphically-derived total sleep time in patients with effectively treated restless legs syndrome with persistent insomnia in a two-arm, double-blind, randomized placebo-controlled crossover 2.5-month trial.

NCT ID: NCT04661306 Completed - Cancer Clinical Trials

The Better Sleep for Supporters With Insomnia Study

BeSSI
Start date: September 30, 2020
Phase: N/A
Study type: Interventional

This study will identify whether - and if so, how - tailoring would increase adoption of and benefit from an interactive internet intervention for insomnia called SHUTi (Sleep Healthy Using the Internet) for cancer caregivers. Participating caregivers' sleep and sleep-related characteristics will be characterized from a baseline assessment; then, caregivers will receive complementary and voluntary access to SHUTi. Among caregivers who choose to use SHUTi, intervention use, perceived appropriateness, and effects on sleep and quality of life will be assessed. Among caregivers who choose not to use SHUTi, reasons and barriers to using the intervention will be assessed.

NCT ID: NCT04653883 Completed - Heart Failure Clinical Trials

Prognostic Impact of Sleep Disorders in Patients : Pro-TSIC Study

Pro-TSIC
Start date: June 1, 2020
Phase:
Study type: Observational

Heart failure (HF) is a common and progressive condition associated with significant morbidity and mortality. Only 25-35% of patients survive 5 years after diagnosis.Sleep disorders are frequently found in this population with up to 94% of patients complaining of sleep disorders. Of these, insomnia and sleep disorders are the most common. The frequency of restless legs syndrome (RLS) varies between 4 and 40% depending on the studies. Patients with HF frequently experience poor sleep quality which is associated with deterioration in quality of life, alertness, and mood. Few studies have examined the prognostic impact of sleep disturbances in this population. A greater morbidity and mortality is observed in the event of poor quality sleep or in the presence of sleep breathing disorders . The investigators therefore propose to evaluate the sleep disorders of patients with HF by self-administered questionnaires, hypothesizing that complaints of poor sleep are linked to a poorer cardiovascular prognosis.

NCT ID: NCT04635085 Completed - Clinical trials for Mild Cognitive Impairment

A Mixed Method Pilot Study for Patients With Mild Cognitive Impairment and Insomnia.

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Dementia is irreversible, incurable and devastating. It is thus imperative to preserve cognition at the pre-dementia stage. Mild cognitive impairment (MCI) refers to the reversible intermediate clinical state between normal age-related cognitive decline and dementia. Because no pharmacological treatments have proved to be effective, risk factor modification remains the cornerstone in preventing progression from MCI to dementia. Insomnia is an emerging risk factor now being associated with cognitive decline, and it affects up to 59% of persons with MCI. Compelling evidence shows that sleep is vital for memory consolidation, and it mediates the deposition of amyloid-β and tau proteins in the brain. Despite these findings, minimal research has done to evaluate sleep-promoting interventions on the cognitive function of persons with MCI. Non-pharmacological interventions remain the treatment of choice for managing insomnia, particularly the older population. These interventions require individuals to actively participate in the treatment process. Yet, the cognitive impairment and neuropsychiatric symptoms in persons with MCI create challenges for them. An empowerment approach with interactive teaching strategies and experiential learning may be the best method of engaging people in the learning process and arousing their inherent capacity to maintain behavioral modifications. This study aims to examine the feasibility and preliminary effects of an empowerment-based cognitive behavioral therapy for insomnia (CBT-I) in persons with MCI and sleep problems. The researchers will compare the effects of this intervention by comparing with the standard care.

NCT ID: NCT04633395 Completed - Insomnia Clinical Trials

Treating Pregnancy Related Insomnia With Music

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

This study aims to examine the effects of 4 weeks music listening at bedtime on sleep quality during the third trimester of pregnancy.

NCT ID: NCT04598425 Completed - Insomnia Clinical Trials

Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Mental Illness

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

Insomnia is common in patients with co-morbid mental illness and sleeping difficulties is a frequent complaint in most psychological disorders. Mental illness may cause sleep problems, however, sleep problems like insomnia, may also cause or exacerbate mental illness. Insomnia may aggravate symptoms of depression, anxiety and fatigue, and reduce daily functioning in patients with co-morbid insomnia and mental illness. This project aims to evaluate a course offered to patients with insomnia and mental illness at Diakonhjemmet Hospital. The course is based on cognitive behavioral therapy, a documented treatment for insomnia.

NCT ID: NCT04592276 Completed - Insomnia Clinical Trials

The Effects of Lactobacillus Plantarum PS128 in Self-Reported Insomniacs

Start date: October 11, 2018
Phase: N/A
Study type: Interventional

To determine whether PS128 (1) reduces the severity of anxiety and depressive symptoms, (2) adjusts autonomic nervous system functioning, and (3) improves sleep quality.

NCT ID: NCT04585425 Completed - Insomnia Clinical Trials

Music for Sleep-onset Insomnia

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The study is a randomized controlled trial evaluating the effect of bedtime music as an early intervention for sleep-onset insomnia in adults. The investigators use a randomized controlled trial design with two parallel groups. All participants receive sleep hygiene advice as standard treatment and participants in the intervention group are additionally asked to listen to a sleep playlist daily at bedtime. Subjective and objective sleep measures are evaluated before and after the 4 weeks intervention period. In addition, follow-up measures of subjective outcomes are assessed 4 weeks after the end of the intervention period.