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Insomnia clinical trials

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NCT ID: NCT05840822 Not yet recruiting - Insomnia Clinical Trials

Evaluating Efficacy and Safety of CBD TPM Capsules for Use in Insomnia

Start date: June 2023
Phase: Phase 3
Study type: Interventional

Insomnia is a common sleep disorder in which a person has difficulty falling asleep or staying asleep or getting good quality sleep. Consequences of insomnia include daytime sleepiness, poor memory function, decline in concentration with negative impacts on social and work activities. Although medical cannabis and cannabis products are widely used worldwide for the management of symptoms associated with insomnia, there is little clinical data available to support the efficacy or utility of CBD in the management of sleep disorders. The proposed study will assess whether nightly doses of 75mg or 150mg of an 8 week period are able to improve patient reported sleep quality when compared to a placebo.

NCT ID: NCT05838430 Recruiting - Insomnia Clinical Trials

Solriamfetol and CBT-I in Patients With Insomnia Disorder

Start date: July 31, 2023
Phase: Phase 4
Study type: Interventional

Medication is FDA approved. The objective of this project is to test the efficacy of solriamfetol for treating insomnia (alone and in combination with Cognitive Behavioral Therapy for Insomnia [CBT-I]). Ultimately, this study will test whether wake extension (regardless of how it is achieved) will consolidate sleep and improve sleep continuity.

NCT ID: NCT05826002 Active, not recruiting - Insomnia Clinical Trials

Optimization of a Digital Self-guided Psychological Intervention for Insomnia: A Randomized Factorial Experiment

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

In a previous pilot study, a digital self-guided intervention for insomnia showed preliminary positive effects on insomnia symptoms. In order to optimize the digital self-guided format, this study will evaluate the added value of three treatment features on treatment engagement and insomnia symptoms. The participants will be adults with insomnia. The trial will be a 2x2x2 randomized factorial experiment, where the following features/factors will be manipulated: an optimized graphical user interface (yes or no), an adaptive treatment strategy (yes or no), and daily prompts to use the intervention (yes or no). The factorial experiment will create 8 equally large groups (1:1:1:1:1:1:1:1), who will receive the different combinations of features. The main outcome will be the effect on treatment engagement.

NCT ID: NCT05822999 Completed - Insomnia Clinical Trials

Study of Efficacy of WELT-IP in Insomnia (WCTP-I-B-01)

Start date: December 15, 2021
Phase: N/A
Study type: Interventional

The purpose of the study was to determine safety and efficacy of WELT-IP in adult insomnia patients. WELT-IP is a cognitive behavioral therapy for insomnia (CBT-I) based digital therapeutics.

NCT ID: NCT05816460 Not yet recruiting - Cancer Clinical Trials

The Sleepio After Cancer Study

SACS
Start date: May 22, 2023
Phase: N/A
Study type: Interventional

This study will recruit women over the age of 18 with a current or prior cancer diagnosis who have clinical insomnia. This study will examine the efficacy of digital cognitive behavioural therapy for insomnia (dCBT-I) compared to sleep hygiene education.

NCT ID: NCT05816304 Not yet recruiting - Depression Clinical Trials

Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-CBTi Study)

HCW-CBTi
Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The COVID-19 pandemic has resulted in increased workload and concerns about personal and family safety for frontline healthcare workers (HCWs), which can lead to decreased well-being and worsening mental health. Sleep disruption is particularly prevalent among HCWs providing frontline COVID-19 care. It can have direct consequences on their cognitive and emotional functioning, as well as on patient safety. Cognitive Behavioral Therapy for insomnia (CBTi) is a first-line treatment for insomnia. It has been shown to improve sleep health and wellbeing in the general population. However, there are significant barriers to delivering CBTi to frontline HCWs, including limited availability of trained sleep therapists and high costs. To address this, a Canada-wide randomized controlled trial is developed to determine the effectiveness of a digital CBTi program on the sleep health, mental health, wellness, and overall quality of life of frontline HCWs caring for COVID-19 patients. This study may provide an easily accessible and scalable sleep health intervention that can be included as part of a national and global response to the COVID-19 pandemic.

NCT ID: NCT05814822 Recruiting - Insomnia Clinical Trials

Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

This study will compare the efficacy of telemedicine-delivered cognitive behavioral therapy for insomnia tailored for people using cannabis for sleep (CBTi-CB-TM) to telemedicine-delivered sleep hygiene education (SHE-TM) on sleep, cannabis use, and daytime functioning. We will also evaluate the effects of CBTi-CB-TM on fundamental sleep regulatory system - homeostatic sleep drive - and its association with clinical outcomes.

NCT ID: NCT05814783 Recruiting - Insomnia Clinical Trials

Clinician Training Program to Integrate Digital CBTI Into Routine Psychotherapy

Start date: August 24, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to pilot test and refine a training program for licensed therapists to promote the integration of digital cognitive behavior therapy for insomnia (dCBTi) into their routine mental health care services.

NCT ID: NCT05812443 Active, not recruiting - Quality of Life Clinical Trials

Assessment of Sleep Quality and Mental Health After Using Meditation

Start date: April 10, 2023
Phase: N/A
Study type: Interventional

This is a randomized controlled trial that intends to verify the effectiveness of the daily practice of meditation before going to sleep for the improvement of sleep, stress, mental health and quality of life of people with sleep problems.

NCT ID: NCT05809544 Completed - Insomnia Clinical Trials

Study of Efficacy of WELT-IP in Insomnia (WCTP-I-B-02)

Start date: October 14, 2022
Phase: N/A
Study type: Interventional

The purpose of the study was to determine safety and efficacy of WELT-IP in adult insomnia patients. WELT-IP is a cognitive behavioral therapy for insomnia (CBT-I) based digital therapeutics.