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Influenza clinical trials

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NCT ID: NCT01560793 Completed - Influenza Clinical Trials

Safety and Immunogenicity of a Novel H5N1 Influenza Vaccine in Healthy Adults Age 18-49 Years

Start date: June 2012
Phase: Phase 1
Study type: Interventional

This study will evaluate the safety and immunogenicity of VAX161B [STF2.HA5 H5N1], a recombinant, inactivated, subunit influenza vaccine given as a two dose regimen at a range of doses.

NCT ID: NCT01554826 Completed - Influenza Clinical Trials

Clinical Trial of the Inactivated Influenza Vaccine (0.25ml Formulation for Pediatric Use)

Start date: March 2009
Phase: Phase 3
Study type: Interventional

The clinical trial was designed to evaluate the immunogenicity and safety against pediatric Inactivated influenza vaccine (Split Virion) (0.25ml formulation) of Hualan administered on infants age 6 months to 36 months.

NCT ID: NCT01554813 Completed - Influenza Clinical Trials

Clinical Trial of Inactivated Influenza Vaccine (0.5ml Formulation)

Start date: May 2006
Phase: Phase 3
Study type: Interventional

The clinical trial was conducted in Jintan City of Jiangsu Province, China in May, 2006. The purpose of the clinical trial was to evaluate the safety and immunogenicity against Hualan's Influenza Vaccine (Split Virion), Inactivated (0.5ml) administered on age 6 months and old population.

NCT ID: NCT01551823 Completed - Influenza Clinical Trials

The Clinical Trial Protocol for the Influenza Virus Vaccine (Split Virion, Inactivated) (Children Forms of Drug)

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and the immunogenicity of Influenza Virus Vaccine (Split Virion, Inactivated)(children forms of drug) that do not contains Preservative.

NCT ID: NCT01551810 Completed - Influenza Clinical Trials

The Clinical Trial Protocol for the Influenza Virus Vaccine (Split Virion, Inactivated)

IVV
Start date: March 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and the immunogenicity of Influenza Virus Vaccine (Split Virion, Inactivated) that do not contains Preservative .

NCT ID: NCT01546935 Withdrawn - Influenza Clinical Trials

Oseltamivir for Influenza Lower Respiratory Tract Infection in Children Under One

Start date: December 2012
Phase: Phase 2/Phase 3
Study type: Interventional

Currently, there is no treatment for children less than one year of age with influenza related lower respiratory tract infection that is either considered standard or registered in any country. This dismal scenario exists even though influenza related LRTI is a significant illness causing morbidity and mortality, especially in children less than 6 months of age. Avian influenza has been reported rarely in children less than one. There are no data in Vietnam and very few data in Thailand on the burden of influenza in children less than one. This young age group suffers high mortality. Oseltamivir may be beneficial in such children. This is basis of this trial.

NCT ID: NCT01545349 Completed - Healthy Clinical Trials

Safety of Lactobacillus Rhamnosus GG Versus Placebo in Elderly Subjects Receiving Live Attenuated Influenza Vaccine

LAIV
Start date: February 2012
Phase: Phase 1
Study type: Interventional

This is a Phase I, randomized controlled trial to evaluate the safety of Lactobacillus rhamnosus GG (LGG) versus placebo in elderly subjects receiving the live attenuated influenza vaccine. Lactobacilli are part of the normal flora of the intestine. LGG is one of several strains of Lactobacilli that is used as a probiotic or microorganism administered to confer "health benefits". Our research is focused on studying the possible therapeutic effects of LGG. The study hypotheses are: 1. LGG or placebo administered twice daily will be safe and well tolerated in elderly subjects who have just received the live attenuated influenza vaccine, 2. The immune response to the influenza vaccine at day 21, 28, and 56 will be higher in the LGG group than the placebo group, 3. The diversity of the microbiota in nasopharyngeal and stool specimens at day 21, 28, and 56 will be greater in the LGG group than the placebo group.

NCT ID: NCT01538940 Completed - Influenza Clinical Trials

Immunogenicity of Influenza Vaccines in HIV-infected Persons in Thailand

Start date: November 1, 2011
Phase: Phase 4
Study type: Interventional

This study will assess the efficacy of a new intradermal formulation of the trivalent inactivated influenza vaccine compared to the standard intramuscular vaccine in HIV-infected men who have sex with men in Bangkok, Thailand. Relative efficacy of the two different formulations of influenza vaccine will be assessed by comparing immunologic responses to vaccine between the two study arms.

NCT ID: NCT01527825 Completed - Influenza Clinical Trials

Immunogenicity and Safety of Different Dosing Schedules of Trivalent Influenza Vaccine in HIV-infected Pregnant Women

Start date: September 2012
Phase: Phase 3
Study type: Interventional

The overall aim of this project is to evaluate the safety and immunogenicity of 3 different dosing options of trivalent influenza vaccine (TIV) vaccination of HIV-infected pregnant women: single dose, double dose (at same time point) and two-doses (1 month apart).

NCT ID: NCT01521416 Completed - Influenza Clinical Trials

Cost of Illness Associated With Influenza in the UK

Start date: June 2011
Phase: N/A
Study type: Observational

The objective of this study is to describe the burden associated with influenza in the UK, from both primary and secondary care perspectives, and to stratify the burden by the annual degree of mismatch between predicted and actual virus strains.