Inflammation Clinical Trial
— CoccinelleOfficial title:
Low Grade Inflammation in Type 1 Diabetes Children
The study propose to measure the inflammation level in type 1 diabetes children with the cytokine analysis compared to non diabetic children of the same sibling and to healthy children.
Status | Completed |
Enrollment | 80 |
Est. completion date | July 2010 |
Est. primary completion date | July 2010 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 2 Years to 17 Years |
Eligibility |
Inclusion Criteria: Type 1 diabetes children group : - Children aged 2 to 17 years - Type 1 diabetes children Controlled group : - Children aged 2 to 17 years - Brother or sister of type 1 diabetes children Exclusion Criteria: - Per os or inhaled corticoid in the previous month of inclusion - Acute infectious disease in the previous week of inclusion - Other chronic disease than diabetes type1 |
Observational Model: Case Control, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
France | Children Hospital, Endocrinology Unit | Bordeaux |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Bordeaux |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Increase of Interleukine 6 in group DTI versus control group | Once at inclusion | No | |
Secondary | Increase of others cytokines (IL1-beta, l'IL-4, l'IL-10 and TNF alpha) and increase of High sensitivity CRP in group DTI versus control group | Once at inclusion | No |
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