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Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome

Infertility Clinical Trial

Official title:
Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome

Clinical Trial Summary

Polycystic ovary syndrome (PCOS) patients are often accompanied by infertility. Non-obese PCOS infertility is more difficult to treat than obese PCOS. The study included non-obese PCOS patients who had not recovered from regular menstruation after six months of metformin treatment. Half of the patients were treated with clomiphene for ovulation induction and half with GnRH pulse therapy.

Clinical Trial Description

To investigate whether GnRH pulse therapy of non-obese PCOS women can improve ovulation rate.The investigators plan to recruit non-obese PCOS women with abnormal GnRH pulse mode not effective of metformin treatment at childbearing age. By using GnRH pulse therapy and Clomiphene therapy. the investigators will intervent the participants for 3 months and to compare outcome in each group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03989024
Study type Interventional
Source RenJi Hospital
Contact Tao TAO, MD
Phone +86-13817701776
Email taotaozhen@hotmail.com
Status Not yet recruiting
Phase Phase 4
Start date July 1, 2019
Completion date December 30, 2021
View Details
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