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Infertility clinical trials

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NCT ID: NCT00977821 Completed - Infertility Clinical Trials

Embryo Developmental Capacity After Egg Banking in an Ovum Donation Program

Start date: September 2009
Phase: Phase 4
Study type: Interventional

For an efficient "egg banking" system, an equally efficient cryopreservation strategy that ensures the viability of the oocytes is required. Very recently, improved and new methods are yielding satisfactory results. In particular, vitrification is providing excellent results for both survival and clinical outcomes. However, to evaluate the over all out come there are other parameters to be considered. In this sense, capacity development of embryos generated after oocyte vitrification is a major factor when assessing the viability of vitrified oocytes. Accordingly, the evaluation of the capacity of vitrified oocytes to reach the blastocyst stage will be highly valuable to fully assess the effectiveness of the "egg banking" and its contribution to ovum donation programs. The aim of this study is to evaluate the developmental capacity of vitrified oocytes by their ability to reach the blastocyst stage. The study includes oocyte donation cycles conducted with vitrified versus fresh oocytes.

NCT ID: NCT00976651 Completed - Infertility Clinical Trials

Low Dose Human Chorionic Gonadotropin: Influence on the Endometrium

Start date: January 2009
Phase: Phase 4
Study type: Interventional

The purpose of the present study is to assess the influence of the administration of low dose hCG on the endometrium. The study is a randomised trial where 2 groups of patients, undergoing a gonadotropin-releasing hormone antagonist protocol for in vitro fertilization, are studied. In addition to the histological findings, by analysing the correlation of the morphological pattern and gene expression profile of human endometrium on the day of oocyte retrieval in patients of both treatment groups, the investigators want to study the implantation potential.

NCT ID: NCT00975117 Completed - Male Infertility Clinical Trials

Spermotrend in the Treatment of Male Infertility

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the administration of the dietary supplement Spermotrend improves spermatogenesis parameters in subjects with male infertility unrelated to major testicular conditions. The duration of this double-blind placebo controlled phase 3 clinical trial will be 24 weeks. The estimated number of males with infertility to be recruited and randomized for the study is 86.

NCT ID: NCT00974649 Completed - Infertility Clinical Trials

Psychosocial Determinants of Continuing or Discontinuing Infertility Treatment: A Psychological Analysis

Start date: November 2007
Phase: N/A
Study type: Interventional

The current study aims to explore and analyse the decision making process of couples in regards to continuing or discontinuing infertility treatment. A longitudinal, prospective cohort design is used which allows the monitoring of patients over a longer period of time. Data will be collected quantitatively (questionnaires) as well as qualitatively (in-depth interviews) to allow for a more specific and in depth experience than can be obtained by using a questionnaire study. Innovative aspects of the study include: 1. exploration of determinants of continuing and discontinuing infertility treatment by using a comprehensive psychological theory (both surface and in-depth) 2. exploration of gender differences in the decision making process in continuing or discontinuing treatment 3. longitudinal and prospective arm of the study will allow to gain insight into the 'process' 4. prediction of continuing/discontinuing treatment based on psychological variables.

NCT ID: NCT00963625 Completed - Infertility Clinical Trials

Comparison of Transfers of Fresh and Thawed Embryos in Normal Responder Patients

Start date: October 2007
Phase: N/A
Study type: Interventional

This study tests the hypothesis that controlled ovarian stimulation impairs endometrial receptivity in normal responders.

NCT ID: NCT00963079 Completed - Infertility Clinical Trials

Comparison of Transfers of Fresh and Thawed Embryos in High Responder Patients

Start date: July 2007
Phase: N/A
Study type: Interventional

This study tests the hypothesis that controlled ovarian stimulation impairs endometrial receptivity in high responders.

NCT ID: NCT00956774 Completed - Infertility Clinical Trials

Comparison of Three Cannulas for Hysterosalpingography

Start date: February 2009
Phase: N/A
Study type: Interventional

The aim of this study is to compare the three commonly used hysterosalpingography (HSG) injection devices on the basis of patient pain perception, total fluoroscopic and procedural time, and side effects in a prospective, randomized study. An important and novel secondary outcome is the comparison of the quality of images obtained with these three devices. The investigators hypothesize that the balloon catheter and cervical vacuum cup will be less painful than the acorn tipped cannula and that there will be no difference in image quality between the three groups.

NCT ID: NCT00953628 Completed - Infertility Clinical Trials

Endometrial Advancement After Rec or u-HCG Triggering

Start date: August 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate any potential advantages of replacing human chorionic gonadotropin (uhCG) with recombinant human chorionic gonadotropin (recHCG) for final oocyte maturation with regard to Ovarian hyperstimulation syndrome (OHSS)pathophysiology, endometrium receptivity and embryo quality and clinical pregnancy.

NCT ID: NCT00924885 Completed - Infertility Clinical Trials

Experience of Pain During Oocyte Retrieval- a Comparison Between Two Aspiration Needles

Start date: June 2009
Phase: N/A
Study type: Interventional

The purpose of the study is to compare the pain experience between the patients that have had their transvaginal oocytes retrieval with ultrasound guidance performed with reduced single lumen needle (Vitrolife Sweden AB, Gothenburg) with the patients that have had follicle aspiration needle, 1.4 outer diameter (Vitrolife Sweden AB, Gothenburg), during the procedure.

NCT ID: NCT00913354 Completed - Infertility Clinical Trials

Acupuncture Versus Placebo Acupuncture During In Vitro Fertilization (IVF) Embryo Transfer

Start date: November 2005
Phase: N/A
Study type: Interventional

During IVF treatment, acupuncture at the time of embryo transfer may improve the pregnancy rate. This study aims to compare IVF pregnancy between two groups of patients that received either acupuncture or sham acupuncture (placebo)around embryo transfer