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Infertility clinical trials

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NCT ID: NCT02365350 Completed - Infertility Clinical Trials

Randomized Clinical Trial on Follicular Flushing in IVF

Start date: January 2015
Phase: N/A
Study type: Interventional

The primary objective is to demonstrate superiority of follicle flushing with the STEINER-TAN Needle® as compared to single lumen aspiration in terms of numbers of COCs retrieved.

NCT ID: NCT02363426 Completed - Infertility Clinical Trials

Vaginal Culture Using INVOcell Compared to Traditional IVF Incubation

Start date: January 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate intravaginal culture using the medical device INVOcell to generate day 5 blastocysts in comparison to traditional IVF.

NCT ID: NCT02363127 Completed - Infertility Clinical Trials

Subcutaneous Progesterone Versus Vaginal Progesterone for Endometrial Preparation in Fresh Donated Oocytes Recipients

Start date: February 2015
Phase: Phase 4
Study type: Interventional

Randomised, prospective, investigator-blinded, controlled, single-centre study to assess the impact on the ongoing pregnancy rate with the use of two progesterones with different administration routes, in recipients of fresh embryos from donor oocytes, undergoing endometrial preparation for fresh embryo transfer.

NCT ID: NCT02362061 Completed - Infertility Clinical Trials

3D Ultrasound Measurement of Junctional Zone Thickness and Its Relation to Implantation Success

Start date: February 2014
Phase: N/A
Study type: Observational

100 patients aged 21-40 years old, diagnosed as primary or secondary infertility . These patients are then assigned to receive fertility treatment (ovulation induction, ICSI, intrauterine insemination and IVF). They undergo a 3D vaginal ultrasound before treatment to measure the junctional zone thickness and followed up after treatment to determine the rate of implantation.

NCT ID: NCT02359695 Completed - Infertility Clinical Trials

Low-dose GH Supplementation Increases Clinical Pregnancy Rate

Start date: October 2013
Phase: Phase 1
Study type: Interventional

The objective of this study is to assess whether a low dose of GH supplementation (0.5 IU/day) increases clinical pregnancy rates in women with a history of POR who failed to become pregnant in two previous IVF cycles.

NCT ID: NCT02358759 Completed - Infertility Clinical Trials

Management of Abnormally Fertilized Zygotes? InVitro Correction of 3PN

Start date: June 2014
Phase: Phase 0
Study type: Interventional

In this newly developed protocol, and idea, is to manage those abnormally developed zygotes from different ART procedures. The investigators developed the plan and requirements needed to select the target extra nucleus or pronuclei to be extruded from fertilized egg in order to maintain developing healthy normal embryo.

NCT ID: NCT02355925 Completed - Infertility Clinical Trials

Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Frozen Embryo Transfer on Cycle Outcomes

Start date: October 2014
Phase: Phase 3
Study type: Interventional

The present study is designed as a pilot study with 150 patients in each group. Data collection form will be filled by the researcher who does not know the type of intervention in each group. Data analysis will be done through descriptive and perceptive statistical methods by using SPSS software version 20 for windows

NCT ID: NCT02354963 Completed - Infertility Clinical Trials

Follicular Activation in Poor Responders

FAPPOR
Start date: November 2014
Phase: N/A
Study type: Interventional

This study aims to assess whether activation of primordial follicles through ovarian cortex fragmentation may increase the number of antral follicles present in the ovary of patients with diminished ovarian reserve. Secondary outcomes include number of oocytes retrieved and pregnancy rates after IVF. Hypothesis; Evaluate whether the proposed intervention increases the pool of antral follicles (potentially stimulable ones).

NCT ID: NCT02351193 Completed - Infertility Clinical Trials

a Predictive Scheme for Poor Responders in IVF Cycles

Start date: January 2011
Phase: N/A
Study type: Observational

While practicing the different assisted reproductive techniques, the investigators are faced daily by the problem of poor responder females, and the debate about predicting its results based on the outcome of the different ORTs used. Due to the cost of AMH as an indicator for ovarian response, the need to re-assess its role was essential in our community, which led us to conduct this prospective multi-center IVF study.

NCT ID: NCT02349945 Completed - Male Infertility Clinical Trials

FSH Receptor Polymorphism p.N680S and Efficacy of FSH Therapy

Start date: January 2011
Phase: Phase 2/Phase 3
Study type: Interventional

CONDITION: Idiopathic male infertility In men with idiopathic infertility, the sperm DNA fragmentation index (DFI) within 12 weeks of FSH therapy and 12 weeks follow-up improves depending on the FSHR genotype as assessed by the non-synonymous SNP rs6166 (wild type or p.N680S). This is a phase II b, multicenter, prospective, open label, one arm, clinical trial stratified according to the patient's genotype. INTERVENTION: FSH therapy (150 I.U. sc every other day for 12 weeks) in infertile men who are homozygous for the wild-type FSHR or the p.N680S allele of the FSHR. Duration of intervention per patient: 12 weeks Primary efficacy endpoint: Sperm DFI. Number of patients with an improvement in DFI > 60% Key secondary endpoint(s): pregnancy, semen parameters, serum levels of inhibin B and AMH.