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Infertility clinical trials

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NCT ID: NCT02399501 Completed - Infertility Clinical Trials

Sonohysterography , 3D Ultrasonography and Hysteroscopy in Assessment of Uterine Factor in Cases of Female Infertility

Start date: March 2015
Phase: N/A
Study type: Interventional

Prospective comparative study including 100 infertile patients with suspected uterine lesion. 2D ultrasound, sonohysterography , 3D ultrasound and hysteroscopy will be done to evaluate uterine cavity.

NCT ID: NCT02397642 Completed - Infertility Clinical Trials

Dual Trigger Versus Booster Dose of HCG

Start date: March 2015
Phase: N/A
Study type: Interventional

To salvage the luteal phase and improve pregnancy rate in antagonist IVF/ICSI cycles triggered with GnRH agonist. Two strategies are compared dual trigger with GnRH agonist plus 1000 IU of HCG or triggering with GnRH and giving a booster dose of HCG (1500 IU) on the day of ovum pickup.

NCT ID: NCT02397551 Completed - Infertility Clinical Trials

Three Small Doses of HCG Versus Booster Dose of HCG on Ovum Pickup Day

Start date: March 2015
Phase: Phase 4
Study type: Interventional

To salvage the luteal phase and improve pregnancy rate in antagonist IVF/ICSI cycles triggered with GnRH agonist. Two strategies are compared supplementing the luteal phase with three small doses (500 IU) of HCG and giving a booster dose of HCG (1500 IU) on the day of ovum pickup.

NCT ID: NCT02393235 Completed - Infertility Clinical Trials

A Comparative Analysis of Arterial Blood Flow in Unexplained Infertility, Tubal Infertility and Fertile Groups

Start date: March 2015
Phase: N/A
Study type: Observational

Factors affecting the success of the treatment of infertility can evaluate before and after embryo transfer in two stages. Most of the patients reach the embryo transfer stage. Unfortunately, the investigators are able to intervene very few of the factors that will affect the success of the post-transfer. All factors and treatments that affect the implantation is vital to identify. Basically, healthy vasculature is essential for a successful implantation. The investigators will try to understand relationship between vascular resistance and type of infertility. The investigators will examine whether the effect of the ovarian uterine and spiral artery resistance over infertility.

NCT ID: NCT02391155 Completed - Infertility Clinical Trials

Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients

needles(opu)
Start date: January 2015
Phase: N/A
Study type: Interventional

In this study, the investigators aimed to evaluate to the efficacy of the needle type used in follicular flushing in oocyte retrieval in the poorest responders undergoing IVF.

NCT ID: NCT02386384 Completed - Infertility Clinical Trials

TNFα and MFG-E8: Novel Biomarkers to Predict Implantation Failure

Start date: March 2015
Phase: N/A
Study type: Observational

Question: Can implantation failure (IF) be predicted prior to in vitro fertilization (IVF)? A pilot, non-interventional, clinical study Prospective, controlled, cohort study

NCT ID: NCT02385396 Completed - Infertility Clinical Trials

Myo-inositol Therapy on the Dynamics of Embryo Development in Patients Suffering From PCOS Undergoing ICSI Treatment

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to analyse the activity of myo-inositol on pregnancy rate, embryo development dynamics and oestradiol and progesterone concentration in blood serum and Superoxide Dismutase (SOD) and catalase concentration in follicular fluid of patients with Polycystic Ovary Syndrome (PCOS) undergoing Intracytoplasmic Sperm Injection (ICSI).

NCT ID: NCT02381184 Completed - Infertility Clinical Trials

Extended Clomiphene Citrate Regimen in Women With Polycystic Ovary Syndrome

Start date: June 2014
Phase: Phase 2/Phase 3
Study type: Interventional

One hundred and thirty six anovulatory women with CC-resistant PCOS were scheduled randomly into two equal groups. Group A (n=68); received CC (100 mg/day from cycle day 3 for 10 days) for up to six cycles. Group B (n=68) underwent LOD and followed up for 6 months. The primary outcome was the ovulation rate in each group; secondary outcomes were midcycle endometrial thickness and serum estradiol, midluteal serum progesterone, and the rates of clinical pregnancy and abortion.

NCT ID: NCT02378584 Completed - Infertility Clinical Trials

Natural Cycle Versus Endometrial Preparation for Healthy Blastocyst Transfer

Start date: February 2015
Phase: N/A
Study type: Interventional

This study evaluates the difference in pregnancy rate transferring a healthy blastocyst in natural or artificial cycle.

NCT ID: NCT02368964 Completed - Infertility Clinical Trials

IVF Treatment in Women With Immature Oocytes in Previous Cycle

Start date: February 1, 2015
Phase: N/A
Study type: Interventional

In standard IVF stimulation cycle,human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH) as a surrogate to only the luteinizing hormone (LH) surge. Yet, the last dose of follicle stimulating hormone (FSH) is usually given between 12-24 hours before the hCG triggering dose.One protocol used at the investigators unit, after a cycle with low proportion of mature oocytes per number oocytes retrieved, is triggering with high dose hCG (500 mcg)-38 hours prior to oocyte aspiration. Lately, new researches showed that dual triggering of final oocyte maturation with a combination of GnRH- agonist and hCG, could improve the live-birth rate of normal responders undergoing the GnRH-antagonist COH protocol Another treatment option is high dose hCG. Only few case reports have described the use of high dose hCG after aspiration of non mature oocytes at a previous cycle. At the investigators IVF unit, patients with previous history of high percentage of immature oocytes retrieved, are triggered at the following cycle, either with double trigger or with high dose of hCG decided by the physician consulting the patient. It is still not known with which way of triggering more mature oocytes is retrieved. The aim of this study is to perform a prospective randomized controlled study in patients with low proportion of mature-MII oocytes oocytes (<75%) per number oocytes retrieved, despite normal response to controlled ovarian hyperstimulation ( COH ) comparing cycles triggered with high dose hCG to those triggered with hCG+GnRH agonist.