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Infertility clinical trials

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NCT ID: NCT02504281 Completed - Clinical trials for Recurrent Miscarriage

Study on the Association Between SXCI and RM and the Possible Genetic Mechanism

Start date: January 2015
Phase:
Study type: Observational

To determine whether there is higher incidence of skewed X chromosome inactivation(SXCI) in the recurrent miscarriage(RM) population compared with normal population, and verify the existing hypothesis of the possible genetic mechanisms underlying the association between SXCI and RM.

NCT ID: NCT02494180 Completed - Infertility Clinical Trials

A Non-inferiority Trial on Pain Relief During Oocyte Retrieval

Start date: March 2016
Phase: Phase 4
Study type: Interventional

The objective of the trial is to compare fentanyl and midazolam vs diazepam and pethidine in terms of the pain levels and post-operative side effects of TUGOR

NCT ID: NCT02491437 Completed - Female Infertility Clinical Trials

A Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Crinone 8% Intravaginal Progesterone Gel 90 mg Daily for Luteal Support in In-Vitro Fertilization (LOTUS II)

LOTUS II
Start date: July 2015
Phase: Phase 3
Study type: Interventional

The purpose of this randomized, two-arm and open label study is to demonstrate that the treatment of a daily dose of 3x10mg dydrogesterone orally is as effective and safe as the daily dose Crinone 8% intravaginal progesterone gel 90 mg for the luteal support in women who are unable to conceive a child and are undergoing IVF. The treatment will start on the day of oocyte retrieval and continue until pregnancy is negative or until week 12 gestation. Patients will be followed during treatment until 30 days after delivery to record any safety and tolerability data of the patient and their newborn (s).

NCT ID: NCT02488434 Completed - Clinical trials for Unexplained Infertility

The Effects of Using Fertile Chip in Sperm Selection for Intracytoplasmic Sperm Injection in Unexplained Infertility

Start date: June 2015
Phase: Phase 3
Study type: Interventional

The aim of the current study is to evaluate to effectiveness of sperm selection by using fertile chip in unexplained infertile couples on intracytoplasmic sperm injection (ICSI) cycles.

NCT ID: NCT02487940 Completed - Subfertility Clinical Trials

Assessment of Intralipid Efficacy in Women With Unexplained Recurrent Implantation Failure

Start date: October 2012
Phase: Phase 4
Study type: Interventional

The study will include 100 women with unexplained recurrent implantation failure undergoing IVF/ICSI cycle. Patients fulfilling the inclusion criteria will be randomised into two groups. Study Group: This group will include 50 women with unexplained recurrent implantation failure undergoing a trial of IVF/ICSI. This group will receive intravenous infusion of intralipid 20%, on the day of oocyte retrieval, a second dose on/ the following day of positive pregnancy test and a final dose 2-3 weeks later when attending for pregnancy scan. Control Group: This group will include 50 women with unexplained recurrent implantation failure undergoing a trial of IVF/ICSI. This group will receive intravenous infusion of placebo, on the day of oocyte retrieval, a second dose on/ the following day of positive pregnancy test and a final dose 2-3 weeks later when attending for pregnancy scan.

NCT ID: NCT02480491 Completed - Infertility Clinical Trials

Study of Free DNA Content of Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment

Start date: January 2014
Phase: N/A
Study type: Observational

Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in intra cytoplasmic sperm injection Treatment Cycles.

NCT ID: NCT02475395 Completed - Sub-Fertility, Male Clinical Trials

Study of the Consumer Use of a New Home Test to Measure Sperm Concentration

Start date: September 2, 2015
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the agreement in measurement of sperm concentration in human semen between lay users with TRAK and a recognized reference method. The study will also include the measurement of matched samples by TRAK when tested by healthcare professionals trained in use of the TRAK device.

NCT ID: NCT02471573 Completed - Infertility Clinical Trials

Freeze All Protocol Versus Fresh Embryo Transfer in Women Undergoing In-vitro Fertilization (IVF)

Start date: June 30, 2015
Phase: N/A
Study type: Interventional

To compare the effectiveness of freeze-all and subsequent frozen embryo transfer (freeze all protocol) with fresh embryo transfer (fresh ET).

NCT ID: NCT02467725 Completed - Infertility Clinical Trials

EnMotion, Embryo's Natural Motion

EnMotion
Start date: June 9, 2015
Phase: N/A
Study type: Interventional

The purpose of the study is to determine if a dynamic embryo microenvironment impacts embryo development and reproductive potential in comparison to static culture.

NCT ID: NCT02466204 Completed - Infertility Clinical Trials

Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients

Start date: June 1, 2015
Phase: Phase 4
Study type: Interventional

A prospective, randomized, controlled study to explore the efficacy and safety of using either corifollitropin alfa 150 mcg or daily recombinant follicle stimulation hormone (FSH) 300 international unit (IU) for the stimulation treatment of subjects undergoing controlled ovarian stimulation prior to IVF. The study is designed as a non-inferiority trial. The sample size for this trial of 400 subjects, in both groups, being treated for one IVF cycle is based upon the primary endpoint of the number of oocytes retrieved.