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Infertility clinical trials

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NCT ID: NCT06324071 Recruiting - Male Infertility Clinical Trials

Study to Verify the Efficacy of a Product Containing 125 mg of TetraSOD® for the Treatment of Male Infertility

Start date: January 8, 2024
Phase: N/A
Study type: Interventional

TetraSOD® is a unique marine phytoplankton (Tetraselmis chuii) SOD-rich ingredient that is grown under patent-protected technology exclusively designed by the company Fitoplancton Marino, S.L. (Spain). In a previous pilot trial, the ability of TetraSOD® (dose: 250 mg/day) to improve semen characteristics in idiopathic infertile men after three months of treatment was assessed, revealing significant improvements in almost all of the analyzed parameters. In a further clinical trial close to finish (ClinicalTrials.gov Identifier: NCT04864314) using the same dose, such positive results have been tested again in a higher number of patients, and additional parameters have been included in order to gain insights into the sperm physiological changes that underpin the improvement in semen quality. In this new clinical trial, an intermediate dose (125 mg/day) is going to be tested in an attempt to determine a range of TetraSOD® dosage being clinically active for the treatment of male infertility.

NCT ID: NCT06322498 Recruiting - Clinical trials for Cesarean Section Complications

Inflammation Markers in Fluid Aspirate From a Scarred Uterine vs. a Normal Uterine Cavity

Start date: January 18, 2023
Phase: N/A
Study type: Interventional

A prospective study that will take place in the hydrosonography clinic, comparing patients with an intact uterus to those who had a caesarean section. Eligible patients will preform a transvaginal ultrasound for evaluation of presence of a niche. After fixation of the transcervical catheter, we will flush 2 ml sterile NaCl 0.9% into the uterine cavity and aspirate the fluid. After collecting all samples, the samples will be snap frozen and stored at -80o C, until they undergo an immunological analysis.

NCT ID: NCT06321107 Recruiting - Infertility Clinical Trials

Long-term Follow-up Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as Reference

Start date: February 29, 2024
Phase:
Study type: Observational

The purpose of this study is to evaluate the safety of a single injection of GenSci094 during Controlled Ovarian Stimulation up to 1 year old of the infants from previous studies.

NCT ID: NCT06319573 Recruiting - Infertility Clinical Trials

The Impact of Personalized Prognostic Counseling on IVF Patient's Experience and Treatment Utilization

Start date: March 19, 2024
Phase: N/A
Study type: Interventional

This study will be conducted in two phases. In the first phase, research subjects will be assigned to receive standard counseling. In the second phase, research subjects will receive Univfy counseling.

NCT ID: NCT06317571 Completed - Infertility Clinical Trials

Evaluation of The Effect of Fertility Support Education Given to Infertile Couples

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

The aim of the this study was to evaluate the effect of fertility support education given to infertile couples before treatment.

NCT ID: NCT06307639 Not yet recruiting - Clinical trials for Male Infertility Due to Azoospermia

Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA

Start date: April 1, 2024
Phase:
Study type: Observational [Patient Registry]

- Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE). - Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples.

NCT ID: NCT06304792 Recruiting - Infertility Clinical Trials

Immediate Versus Postponed Single Blastocyst Transfer in Programmed or Stimulated Cycle Frozen Embryo Transfer

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial is to examine whether single blastocyst transfer in the first cycle after oocyte retrieval (immediate) is non-inferior to single blastocyst transfer in a subsequent cycle (postponed) in stimulated or programmed cycle frozen embryo transfer (FET). The primary outcome is live birth rate.

NCT ID: NCT06304220 Not yet recruiting - Infertility, Female Clinical Trials

Comparison of Two PPOS Models for Pituitary Suppression

Start date: April 2024
Phase: N/A
Study type: Interventional

The scarcity of evidence regarding the interchangeable use of different progestogens poses challenges, particularly in international egg donation and fertility preservation programs where standardizing protocols is crucial for achieving consistent efficacy, efficiency, and safety outcomes. Consequently, there's a pressing need for clinical studies to assess the effects of various progestogens on clinical outcomes in controlled ovarian hyperstimulation cycles. This study, a pioneering effort, aims to compare the effects of two progestogens on oocyte performance, safety, and efficiency in an egg donation program involving young, healthy, normo-responding patients.

NCT ID: NCT06300229 Not yet recruiting - Infertility, Male Clinical Trials

NAPO - Novel Approach for Oligospermia

NAPO
Start date: March 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This randomized controlled trial aims to assess whether treatment with denosumab can improve semen quality in infertile men selected by serum anti-mullerian hormone (AMH) as a positive predictive biomarker, and with severely impaired semen quality (concentrations between 0.01 million/mL to 2 million/mL).

NCT ID: NCT06297070 Recruiting - Fertility Issues Clinical Trials

Lifestyle Care for Fertility Outcome Evaluation

PROWESS
Start date: January 24, 2024
Phase:
Study type: Observational

An observational outcome evaluation of the Lifestyle Care for Fertility program.