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NCT ID: NCT03756506 Completed - Infection Clinical Trials

The Use of a Novel Microbicidal Liquid Polymer for the Reduction of Pin Track Infection

Start date: November 7, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate additional clinical uses for the polymer, which is a FDA approved, 510k, medical device, but has not been approved for use on patients with pin track sites as a way to lower the infection rate and is investigational for this purpose. The approved uses include wound care and post-operative care. About 13 subjects will take part in this study.

NCT ID: NCT03750721 Completed - Clinical trials for Bone and Joint Infection

Staphylococcal Acute Post-Operative PJI Treated With 'DAIR' And Impact Of Rifampin

IPASTAPH
Start date: April 1, 2018
Phase:
Study type: Observational

S. aureus and coagulase-negative staphylococci are the most frequent bacteria responsible for PJI (prosthetic joint infection). The aim of this study is to describe the use of rifampicin.

NCT ID: NCT03750162 Completed - Clinical trials for Root Canal Infection

Bacteria Elimination in Retreatment Cases Using Different Disinfection Techniques

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Nonsurgical root canal retreatment may become essential when the initial endodontic treatment fails because of the persistent intracanal or extracanal infections.It has been stated that the one of the main cause of posttreatment disease is the persistent or reintroduced microorganism such as enterococcus faecalis. Supplementary disinfection techniques such as irrigation agitation methods can help elimination of bacteria from root canal systems. The aim of this in vivo study was to compare the effect of passive ultrasonic irrigation, manual dynamic activation and photodynamic therapy in reducing bacterial load in endodontic retreatment cases with periradicular lesion by using polymerase chain reaction (PCR)in a single visit root canal treatment.

NCT ID: NCT03748992 Completed - Clinical trials for Nontuberculous Mycobacterium Infection

A Proof of Concept Study of Inhaled Nitric Oxide for Adults With Pulmonary Non-Tuberculous Mycobacterial Infection

Start date: January 28, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of open-label exposure of gNO in patients with NTM lung disease. Subjects will receive the study drug by inhaling through a nasal mask. Subjects will be treated for 3 weeks (5 days per week) and followed monthly for 3 months.

NCT ID: NCT03741322 Completed - Clinical trials for Respiratory Tract Infections

A 24 Month Observational Study of Infants 3-24 Months, Who Suffer an Acute Episode of Respiratory Infection and Wheezing Illness

BIOPA
Start date: December 12, 2018
Phase:
Study type: Observational

This study will identify infants between the age of 3 and 24 months of age who are experiencing one of their first acute respiratory infections with confirmed wheezing. Infants who are also confirmed to be wheezing and whose caregiver signs consent will be enrolled from a primary care clinic, emergency room or hospital.

NCT ID: NCT03740802 Completed - Infection Clinical Trials

Hypophosphatemia as a Predictor in Surgical Resuscitation Sepsis

Start date: January 26, 2018
Phase:
Study type: Observational

Retrospective study in the surgical intensive care unit of the Brest Teaching Hospital (France) during a 6-months period (January 2015 -May 2015) to study the independent association between hypophosphatemia and 28-day infection.

NCT ID: NCT03728608 Completed - Infection Clinical Trials

Optimal Feeding Tube Dwell Time in VLBW Infants to Reduce Feeding Tube Contamination

Start date: May 10, 2017
Phase: N/A
Study type: Interventional

The study team will determine whether a decreased feeding tube dwell time will reduce feeding tube contamination

NCT ID: NCT03720314 Completed - Clinical trials for Irritable Bowel Syndrome

Microbiota Profiling in IBS

IBSQUtrition
Start date: September 6, 2018
Phase:
Study type: Observational

This study investigates differences in microbiota profiles and metabolite levels between mild and severe IBS patients, compared to matched healthy controls. Two fecal samples, with one month in between, will be analyzed. Secondary parameters such as dietary intake, quality of life and stool pattern will be assessed.

NCT ID: NCT03717090 Completed - Clinical trials for Prosthetic Joint Infection

Rapid Diagnosis of Prosthetic Joint Infection by Matrix-assisted Laser Desorption

Start date: December 1, 2016
Phase:
Study type: Observational

This is a prospective cohort study. All patients presenting for periprosthetic joint infection and requiring debridement only or resection arthroplasty will be eligible. The synovial joint fluid will be sampled before the arthrotomy at the operation room. The purpose of this study will be to evaluate that 1) the concordance of organism identification by the direct identification of MALTI-TOF MS versus routine identification of MALTI-TOF MS and conventional cultures and 2) the timing of preliminary strain identification by the direct identification of MALTI-TOF MS, routine identification of MALTI-TOF MS and conventional cultures in patients with periprosthetic joint infection.

NCT ID: NCT03716804 Completed - Clinical trials for Antibiotic Resistant Infection

Establish the Relationship Between Shift in Prescribing Pattern and Associated Shift in Sensitivity Pattern of Causative Microbes in UTI Patients in a Closed Community

UTI
Start date: June 6, 2018
Phase: Phase 4
Study type: Interventional

To establish a relationship between changed prescribing pattern and associated shift in sensitivity trend of causative microbes in patients of uncomplicated urinary tract infection in a closed community