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Root Canal Infection clinical trials

View clinical trials related to Root Canal Infection.

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NCT ID: NCT06339905 Completed - Clinical trials for Root Canal Infection

The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This study evaluates postoperative pain and radiographic healing of asymptomatic posterior teeth with chronic apical periodontitis following root-canal treatment performed using EndoActivator for irrigation activation.

NCT ID: NCT06035185 Not yet recruiting - Endodontic Disease Clinical Trials

Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical Lesion

Start date: December 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to define the role of apical shaping and irrigation activation on root canal cleanliness. The main questions it aims to answer are: - does the effectiveness of irrigation activation depends on apical shaping? - can a similar success be achieved by increasing apical shaping without irrigation activation Participants will [describe the main tasks participants will be asked to do, treatments they'll be given and use bullets if it is more than 2 items].

NCT ID: NCT06027931 Active, not recruiting - Clinical trials for Root Canal Infection

Traditional Versus Conservative Access Cavities Cleaning Ability

Start date: September 12, 2022
Phase: N/A
Study type: Interventional

Aims of the study: 1. Assess the clinical and radiographical outcomes (success/failure) of root canal treatments performed after traditional vs conservative access cavities in permanent posterior teeth after one-year follow-up. 2. Assess the level of disinfection in root canals accessed by traditional vs conservative access cavities in permanent posterior teeth before obturation. Null hypothesis: 1. There is no difference in the clinical and radiographical outcomes of root canal treatments performed after traditional and conservative access cavities preparation in posterior teeth after one-year of follow-up.

NCT ID: NCT05959629 Recruiting - Endodontic Disease Clinical Trials

Erbium, Chromium: Yttrium, Scandium, Gallium, Garnet (Er,Cr:YSGG) Laser in Root Canal Disinfection

Start date: October 11, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to develop a protocol for biofilms disinfection with a FDA cleared, clinically approved and commercially available Er,Cr:YSGG laser treatments. This protocol will be testing local single topical application of Lasers within the canal system in patients going through routine endodontic treatment, evaluate its potential as anti-biofilm treatment and compare it to other currently used antibacterial protocols.

NCT ID: NCT05778227 Completed - Clinical trials for Apical Periodontitis

Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.

Start date: November 16, 2021
Phase: N/A
Study type: Interventional

The basic aim of root canal treatment is to reduce the microbial content and prevent further recontamination in the canal. Every tooth has a variable, complex canal anatomy consisting of ramifications, accessory and lateral canals. Instrumentation alone cannot reach all the areas for cleaning.The objectives of this research study is to observe and compare the effect of irrigation with smearOFF , etidronic acid/ hypochlorite and other irrigants on sealer penetration and dentin erosion of root dentin by using scanning electron microscope (SEM) and Energy Dispersive X-Ray Analysis (EDX). Hundred extracted premolar teeth is subjected to root canal instrumentation. The endodontic procedure is done with protaper gold files. Initial irrigation is done by 5% sodium hypochlorite. Samples are divided into five groups. Each group consists of twenty single rooted premolars based on final irrigation regimen. There will be four experimental groups which are as follows (1) 17% EDTA (2) SmearOFF 3) Maleic acid (4) HEBP/NaOCL. Whereas, saline will be the control group. After the preparation and final irrigation of all teeth with experimental irrigants, sterile saline is used to flush all canals and dried using paper points. After final irrigation teeth are further divided into two groups (A) Sealer penetration (B) Dentin erosion. In both the groups standardization of root length, cleaning and shaping procedure are the same. For sealer penetration, obturation is done by warm vertical using AH plus sealer. Samples are incubated at 37º Celsius (°C) and 100% humidity for 7 days. The samples are marked and divided into three horizontal section at 2mm, 5mm and 8mm. Using SEM, measure the maximum depth of sealer penetration on each side that is buccal, lingual, mesial and distal and take the mean for each section of sample. For dentin erosion (B) samples are divided sagitally & buccolingually into two halves. The half containing the most visible part of apical area is taken and than examined using EDX. One-Way ANOVA-test will be used to compare mean values of multiple groups. Tukey's post hoc test will be used to determine the group with significance at P≤0.05. Two observers will evaluate the results using kappa statistics.

NCT ID: NCT05763420 Enrolling by invitation - Clinical trials for Root Canal Infection

Clinical Efficacy of AH Plus Bioceramic Sealer

Start date: August 7, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the efficacy and outcome of sealer-based obturation (SBO) using a new calcium silicate sealer in comparison with warm vertical compaction (WVC) using a resin-based sealer, which is the current gold standard.

NCT ID: NCT05714384 Enrolling by invitation - Clinical trials for Root Canal Infection

Outcome of Calcium Silicate Sealer-based Obturation in Root Canal Retreatment

Start date: March 5, 2023
Phase:
Study type: Observational

This study will evaluate the outcome of calcium silicate sealer-based obturations in root canal retreatment.

NCT ID: NCT05681221 Not yet recruiting - Clinical trials for Root Canal Infection

Clinical and Radiographic Evaluation of the Synergistic Effect of Nano Silver Particles and Calcium Hydroxide Versus Triple Antibiotic Paste as Antibacterial Agents for Lesion Sterilization and Tissue Repair (LSTR) in Necrotic Primary Molars

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

Could the clinical and radiographic success of Nano Silver Particles and Calcium Hydroxide be comparable to that of Triple Antibiotic Paste as antibacterial agents for Lesion Sterilization and Tissue Repair (LSTR) in necrotic second primary molars?

NCT ID: NCT05648305 Completed - Clinical trials for Root Canal Infection

The Influences of Root Canal Complexity and Clinician Training on Root Canal Treatment Outcomes.

Start date: January 1, 2015
Phase:
Study type: Observational

This is an observational study that assess the impacts of (a) root canal treatment complexity and (b) clinical training on (1) root canal treatment success and (2) tooth survival, in a United Kingdom Armed Forces cohort.

NCT ID: NCT05633537 Completed - Clinical trials for Root Canal Infection

Clinical & Radiographic Evaluation of Zinc Oxide-Ozonated Oil as a New Primary Root Canal Filling

Start date: July 4, 2021
Phase: N/A
Study type: Interventional

Preserving primary teeth is essential for many aspects such as the child's growth and development, esthetic, functional, psychological, and dental arch integrity aspects. a randomized blinded controlled clinical trial aimed to evaluate the clinical and radiographic success of Zinc Oxide-Ozonated Olive Oil as root canal filling materials for primary molars compared to Zinc Oxide-Olive Oil & Zinc Oxide-eugenol. 90 primary molars of 30 children aged between 4-8 years with pulpally involved primary molars, are equally divided into 3 groups which treated with Zinc Oxide-Ozonated Olive Oil , zinc oxide -olive oil and zinc oxide eugenol as obturation materials following pulpectomy procedure. The subjects were followed up clinically and radiographically at 3, 6 and 12 months.