Clinical Trials Logo

Infection clinical trials

View clinical trials related to Infection.

Filter by:

NCT ID: NCT04906304 Completed - Clinical trials for Cytomegalovirus Infections

Comparison of Safety and Efficacy of de Novo Everolimus

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Nowadays, de novo everolimus regimen in renal transplant patients is considered for reduction of cyclosporine dose and it is mentioned that this regimen not only has similar safety and efficacy, but also could prevent Cytomegalovirus (CMV )infections. So, the aim of this study was comparison of safety and efficacy of de novo everolimus plus low dose of cyclosporine with standard dose of cyclosporine plus cellcept on CMV virus infections prevention in renal transplant patients.

NCT ID: NCT04895657 Completed - Clinical trials for Gram-Negative Infections

Extended-infusion of Piperacillin-Tazobactam Versus Intermittent Infusion

Start date: July 27, 2018
Phase: Phase 4
Study type: Interventional

Continuous-infusion of piperacillin/tazobactam over 4 hrs instead of 30-minute intermittent dosage regimen has shown observable outcomes. Our objective is to assess whether continuous infusion of piperacillin/tazobactam is superior in terms of efficacy, safety and cost to the intermittent regimen to treat suspected or proved infections due to gram negative bacteria. The setting is Critical Care Medicine Department at Cairo University Hospitals. Methods A prospective randomized comparative study.

NCT ID: NCT04893694 Completed - SARS-CoV2 Infection Clinical Trials

the Prevalence of Oral Manifestation in Patients With SARS-CoV2 Infection

Start date: May 20, 2021
Phase:
Study type: Observational

The SARS-Cov2 virus was identified in china at the end of 2019 and spread worldwide causing a global pandemic. Current research showed that SARS-Cov2 virus invades human cells via the receptor angiotensin-converting enzyme 2 (ACE2) through scRNA-seq data analyses. The study identified the organs that are at risk and are vulnerable to SARS-CoV-2 infection. Therefore, cells with ACE2 receptor distribution may become host cells for the virus and cause inflammatory response in related organs and tissues, such as the tongue mucosa and salivary glands. These results suggest that oral mucosa could be a target of SARS-CoV-2 infection

NCT ID: NCT04892238 Completed - Clinical trials for Helicobacter Pylori Infection

Helicobacter Pylori Infection Occurrence in Russia

Start date: January 1, 2017
Phase:
Study type: Observational

This study is planned to reveal the occurrence rate of H.pylori infection in ambulatory settings' patients in Russia and to compare the occurrence rates in different years in treatment-naïve and previously treated subjects.

NCT ID: NCT04891276 Completed - Clinical trials for Diabetic Subjects With Hospital Stays

Impact of COVID-19 Infection and Confinement on Diabetic Ulcer Management and Amputation Risk

COROPIEDIAB
Start date: October 16, 2020
Phase:
Study type: Observational

In the context of the COVID-19 pandemic, a number of factors, including the lockdown that was imposed to limit the spread of infection, the fear of being contaminated during hospital consultations and the difficulty in accessing general practitioners may have led to delays in the referral of patients to facilities specialized in the management of diabetic ulcers. Since the beginning of the coronavirus pandemic and during the first lockdown, we observed a clear decrease in hospitalizations and consultations for diabetic ulcers. Patients who had regular follow-up for the management of their diabetic ulcers cancelled their scheduled appointments for fear of being contaminated in the hospital. It is feared that the current epidemic context has favored the delay of referral of patients with diabetic ulcers to specialized facilities, with consequences on the prognosis of these patients and the risk of lower limb amputation. In this context, this project aims to evaluate the impact of confinement on emergency hospitalizations for foot wounds and the effects on the risk of amputation during the lockdown and the three months following the end of the lockdown. Our hypothesis is that the lockdown led to a decrease in hospitalizations for foot wounds, resulting in a delay in the management of these patients, and potentially leading to an increase in the number of amputations in the three months following the end of the lockdown. In parallel, we will also study the impact of confinement on deferrable hospitalizations (glycemic imbalance, assessment of diabetic complications...) or theoretically non-deferrable (diabetic comas, ketoacidosis, diagnosis of type 1 diabetes, acute coronary syndrome, stroke...) of diabetes mellitus. This will allow us to evaluate whether our findings relative to diabetic ulcers could be extended to other complications of diabetes.

NCT ID: NCT04883801 Completed - Covid19 Clinical Trials

Clinical Outcomes of Newborns Born to Pregnant Women With and Without COVID-19

Start date: March 11, 2020
Phase:
Study type: Observational

A case-control trial was conducted to test the early postpartum period clinical outcomes of newborns born to pregnant women with and without COVID-19.

NCT ID: NCT04874363 Completed - Covid19 Clinical Trials

The Effects of Smoking on Mortality in Patients With Acute Respiratory Syndrome Coronavirus 2 Infection

Start date: March 15, 2020
Phase:
Study type: Observational

This is a retrospective single centered study that was done in the ICU on patients with Covid-19 between 16th of March -16th of May in 2020 Retrospective records will be examined by examining the electronic data files of the patients. There were two groups as smoker and non-smoker.

NCT ID: NCT04867226 Completed - Clinical trials for Coronavirus Infection

Effectiveness of Colchicine Among Patients With COVID-19 Infection

Start date: May 8, 2021
Phase: Phase 2
Study type: Interventional

In November 2019, there were a lot of cases of an acute respiratory illness (then named at February 11th as COVID_19) which first case was reported in Wuhan, China,The SARS COV-2 had been spread in a fast way to involve whole world, As it's obvious that Colchicine is a drug that is most commonly and widely used to treat and prevent acute attacks of Gout, other crystal induced arthropathy,colchicine has important role in inhibiting activation of NLRP3 inflammasome these lead to decrease cytokine production , aim of study To evaluate whether colchicine is effective in the treatment of COVID-19 cases. And to measure the effectiveness of colchicine in alleviating and controlling pulmonary and extra pulmonary complications of COVID-19

NCT ID: NCT04865003 Completed - Inflammation Clinical Trials

Prognostic Factors for Descending Necrotizing Mediastinitis Development in Deep Space Neck Infections

Start date: January 1, 2014
Phase:
Study type: Observational

Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections.

NCT ID: NCT04862403 Completed - Newborn; Infection Clinical Trials

The Effect of Umbilical Cord Clamping Distance

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

A randomized control trial was conducted to test the effect of umbilical cord clamping distance on cord separation time and umbilical cord microbial colonization in neonates.