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Infant, Newborn, Disease clinical trials

View clinical trials related to Infant, Newborn, Disease.

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NCT ID: NCT05520164 Completed - Pain Clinical Trials

Effect of Maternal Heart Sound on Crying Time and Pain Level in Newborns During Heel Blood Collection

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

This study was carried out to determine the effect of maternal heart sound listened to by newborns during heel blood collection on pain level and crying time.

NCT ID: NCT05510271 Completed - Pain, Acute Clinical Trials

Pain in Newborn Heel Blood Collection

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study was conducted to evaluate the effect of white noise and therapeutic touch on pain in newborn heel blood collection.Questions including the sex of the newborns, postnatal age, gestational age, birth weight, height, head and chest circumference, feeding style, nutritional status in the last half hour, and previous heel blood collection were collected with the "Information Form".The Newborn Infant Pain Scale (NIPS) was used to evaluate the pain levels of newborns.

NCT ID: NCT05493527 Recruiting - Clinical trials for Respiratory Tract Diseases

Noninvasive High Frequency Oscillatory Ventilation as a Post-extubation Respiratory Support in Neonates

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

A randomized controlled trial comparing Noninvasive high frequency oscillatory ventilation (NHFOV) and Noninvasive positive pressure ventilation (NIPPV) as post-extubation respiratory support in preterm neonates with respiratory distress syndrome(RDS)

NCT ID: NCT05343403 Active, not recruiting - Premature Birth Clinical Trials

Parental Participation on the Neonatal Ward - the neoPARTNER Study

neoPARTNER
Start date: March 7, 2022
Phase:
Study type: Observational

Objective: To investigate the effect of FCR as part of the FICare principles during hospital stay, on parental stress at discharge in parents of preterm or ill infants admitted to the neonatal ward for >7 days as compared to standard medical rounds (SMR) without parents as part of standard neonatal care (SNC).

NCT ID: NCT05217186 Completed - Cerebral Palsy Clinical Trials

Associations Between Early Neonatal Neuroimaging, Hammersmith Infant Neurological Examination and General Movements

highrisk
Start date: September 15, 2020
Phase:
Study type: Observational [Patient Registry]

High risk infant is defined as infant with a negative history of environmental and biological factors, which can lead to neuromotor development problems. It is a heterogeneous group of premature infants born under thirty-seven weeks of age, with infants with low birth weight, term or developmental retardation for various reasons. Therefore, preterm infants with low birth weight can survive with a neurological sequelae such as cerebral palsy (CP), epilepsy, hearing and vision loss, mental retardation, speech and speech problems, and learning difficulties. The clinical diagnosis of CP, which can be observed in high-risk infants, is based on the combination of some neuroimaging and neurological examinations and assesments like neonatal imaging, general movements (GMs) and Hammersmith Infant Neurological Examination (HINE).

NCT ID: NCT04848090 Enrolling by invitation - Genetic Disease Clinical Trials

Genome Sequencing in the Intensive Care Unit Population

PISCES
Start date: July 13, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to understand how the use of whole genome sequencing (WGS) may be able to increase the speed with which a diagnosis is made for patients in an intensive care unit population. This is not an assessment of a new device, test, or technology. This project is an investigation of the utility of this technology in clinical care when compared to standard of care testing. The study will look at the ability to more quickly diagnose a patient (time to diagnosis and efficacy of testing) as compared to standard of care testing. The study will also look at the impact of WGS on patient outcomes and cost of clinical care.

NCT ID: NCT04823026 Completed - Sepsis Clinical Trials

Host RNA Profiles to Detect Infections in Young Infants

CHILD_YIC
Start date: May 15, 2020
Phase:
Study type: Observational

This study seeks to identify and test host RNA expression profiles as markers for infections in young infants. Preliminary studies have shown high sensitivity and specificity for the discrimination of bacterial from non-bacterial infections in children, but the method has only been investigated in a limited number of young infants. The study aims to include 65 young infants with serious bacterial infections. The samples will be analysed by RNA sequencing. New diagnostic tools may help reduce unnecessary antibiotic treatment, antibiotic resistance, side-effects, hospitalisation and invasive procedures.

NCT ID: NCT04812847 Completed - Clinical trials for Infant Newborn Disease

Multidrug Resistant Gram-negative Pathogen Infections in High Risk Neonates in the Northeast of Mexico

InfGNMDR-Neo
Start date: June 1, 2021
Phase:
Study type: Observational

The main objective of this project is to establish a prospective cohort to measure the Gram-negative infection burden in neonates under special care in a regional referral hospital, and to characterize all microorganisms isolates from these subjects at the phenotype and genotype level, specifically in relation to the expression of multi-drug resistance (MDR) associated genes (Molecular characterization of Gram-negative MDR isolates).

NCT ID: NCT04792099 Completed - Hypoxia Clinical Trials

CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial

COCO
Start date: August 16, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if in preterm infants < 34 weeks' gestation at birth receiving respiratory support with continuous positive airway pressure (CPAP) or nasal cannula (NC), CPAP compared with NC will decrease the number of episodes with oxygen saturations less than 85% of ≥10 seconds in a 24-hour randomized controlled trial. This will be a randomized controlled trial with a 1:1 parallel allocation of infants to CPAP or NC oxygen using stratified permuted block design.

NCT ID: NCT04748159 Completed - Clinical trials for Infant, Premature, Diseases

Effects of Prone Positioning on Vital Parameters in Infants With Acute Bronchiolitis

Start date: January 3, 2020
Phase: N/A
Study type: Interventional

This intervention study is designed to evaluate short-term effects (within one hour) of prone position on vital signs in infants under 12 months of age with acute RSV bronchiolitis. The primary objective is to investigate whether respiratory rate changes in prone position. Secondary endpoints are changes in oxygen saturation (SpO2), transcutaneous carbon dioxide partial pressure (pCO2), heart rate, and respiratory symptoms assessed by the Modified Tal Score (MTS).